Transkripcijski faktor 3 Hes porodice bHLH jest protein koji je kod ljudi kodiran genom HES3 sa hromosoma 1.[5]
Kratke činjenice Identifikatori, Aliasi ...
HES3 |
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Identifikatori |
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Aliasi | HES3 |
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Vanjski ID-jevi | OMIM: 609971 MGI: 104877 HomoloGene: 7358 GeneCards: HES3 |
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Ontologija gena |
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Molekularna funkcija | • vezivanje sa DNK • transcription factor binding • protein dimerization activity • GO:0000980 RNA polymerase II cis-regulatory region sequence-specific DNA binding • GO:0001078, GO:0001214, GO:0001206 DNA-binding transcription repressor activity, RNA polymerase II-specific • GO:0001200, GO:0001133, GO:0001201 DNA-binding transcription factor activity, RNA polymerase II-specific • RNA polymerase II transcription regulatory region sequence-specific DNA binding • GO:0001106 transcription corepressor activity • sequence-specific DNA binding • sequence-specific double-stranded DNA binding
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Ćelijska komponenta | • jedro
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Biološki proces | • hindbrain morphogenesis • trochlear nerve development • midbrain-hindbrain boundary morphogenesis • GO:0045996 negative regulation of transcription, DNA-templated • in utero embryonic development • GO:1901227 negative regulation of transcription by RNA polymerase II • GO:0009373 regulation of transcription, DNA-templated • regulation of timing of neuron differentiation • regulation of neurogenesis • oculomotor nerve development • transcription, DNA-templated • midbrain development • GO:0003257, GO:0010735, GO:1901228, GO:1900622, GO:1904488 positive regulation of transcription by RNA polymerase II • neural tube development • somitogenesis • Notch signaling pathway • Ćelijska diferencijacija • anterior/posterior pattern specification
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Izvori:Amigo / QuickGO |
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Ortolozi |
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Vrste | Čovjek | Miš |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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RefSeq (mRNK) | | |
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RefSeq (bjelančevina) | | |
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Lokacija (UCSC) | Chr 1: 6.24 – 6.25 Mb | Chr 4: 152.37 – 152.38 Mb |
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PubMed pretraga | [3] | [4] |
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Wikipodaci |
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Zatvori