异硫氰酸苄酯 (BITC) 是一种异硫氰酸酯，存在于十字花科的植物中。
异硫氰酸苄酯可以在葱芥、pilu油和番木瓜种子中找到[2]，是黑芥子酶分解苄基硫代葡萄糖苷的主要产物。
人们发现异硫氰酸苄酯和其他异硫氰酸酯通常通过p21/WAF1基因的表达，[3]对in vitro的胰腺癌变具有保护作用。[4]最近发表的一项研究表明，它对饮食诱导的肥胖小鼠模型中的肥胖、脂肪肝和胰岛素抵抗有抑制作用。[5]
Nakamura, Yoshimasa; Yoshimoto, Motoko; Murata, Yoshiyuki; Shimoishi, Yasuaki; Asai, Yumi; Park, Eun Young; Sato, Kenji; Nakamura, Yasushi. Papaya Seed Represents a Rich Source of Biologically Active Isothiocyanate. Journal of Agricultural and Food Chemistry. 2007, 55 (11): 4407–13. PMID 17469845. doi:10.1021/jf070159w. Moon, Sung-Kwon; Choi, Yung-Hyun; Kim, Cheorl-Ho; Choi, Won-Seok. P38MAPK mediates benzyl isothiocyanate-induced p21WAF1 expression in vascular smooth muscle cells via the regulation of Sp1. Biochemical and Biophysical Research Communications. 2006, 350 (3): 662–8. PMID 17026958. doi:10.1016/j.bbrc.2006.09.092. Kuroiwa, Yuichi; Nishikawa, Akiyoshi; Kitamura, Yasuki; Kanki, Keita; Ishii, Yuji; Umemura, Takashi; Hirose, Masao. Protective effects of benzyl isothiocyanate and sulforaphane but not resveratrol against initiation of pancreatic carcinogenesis in hamsters. Cancer Letters. 2006, 241 (2): 275–80. PMID 16386831. doi:10.1016/j.canlet.2005.10.028.
