免疫相關GTP酶家族M蛋白

免疫相關GTP酶家族M蛋白
識別號
別名	IRGM；, IFI1, IRGM1, LRG-47, LRG47, immunity-related GTPase M, immunity related GTPase M
外部ID	OMIM：608212 MGI：1926262 HomoloGene：78363 GeneCards：IRGM
相關疾病
	inflammatory bowel disease 19
基因位置（人類）
染色體	5號染色體
終止	150,900,736 bp
基因位置（小鼠）
染色體	小鼠11號染色體
終止	58,113,608 bp
基因本體
分子功能	• 核苷酸結合; • GTP binding; • 水解酶活性; • 血漿蛋白結合; • protein kinase binding; • protein serine/threonine kinase activator activity; • CARD domain binding; • BH3 domain binding; • GTPase activity;
細胞組分	• phagocytic vesicle membrane; • autophagosome membrane; • cell projection; • phagocytic cup; • 細胞膜; • 膜; • cytoplasmic vesicle; • Golgi membrane; • 粒線體; • 高基氏體; • 細胞質基質; • endoplasmic reticulum membrane;
生物學過程	• 自噬; • inflammatory response; • immune system process; • autophagosome assembly; • positive regulation of protein phosphorylation; • positive regulation of autophagy; • positive regulation of peptidyl-threonine phosphorylation; • protein destabilization; • positive regulation of peptidyl-serine phosphorylation; • regulation of protein-containing complex assembly; • 先天免疫系統; • protein stabilization; • defense response to Gram-negative bacterium; • positive regulation of interferon-gamma-mediated signaling pathway; • regulation of protein complex stability; • protein lipidation involved in autophagosome assembly; • CAMKK-AMPK signaling cascade; • nucleotide-binding oligomerization domain containing 2 signaling pathway; • cellular response to lipopolysaccharide; • positive regulation of autophagosome maturation; • positive regulation of protein serine/threonine kinase activity; • defense response; • cellular response to interferon-beta;
	Sources:Amigo / QuickGO
直系同源
	345611
	54396
	ENSG00000237693
	ENSMUSG00000069874
	A1A4Y4
	Q9Z1M2
	NM_001145805; NM_001346557
	NM_019440
	NP_001139277; NP_001333486
	無資料
	維基資料
檢視/編輯人類	檢視/編輯小鼠

免疫相關GTP酶家族M蛋白（英語：Immunity-related GTPase family M protein，IRGM），亦稱為干擾素誘導蛋白1（英語：interferon-inducible protein 1，IFI1），是人體IRGM基因表現的一種酶^[6]。