人絨毛膜促性腺激素(英語:Human chorionic gonadotropin,簡寫為hCG)是一種糖蛋白激素,由胎盤的滋胚層細胞分泌,主要功能是刺激黃體,有利於雌激素和黃體酮持續分泌,以促進子宮蛻膜形成,使胎盤生長成熟。胚胎一旦著床後,滋胚層細胞就會開始分泌hCG,所以可以透過血中或尿中hCG值來判斷妊娠。
由244個胺基酸殘基組成,分子量36.7kDa,大小7.5×3.5×3納米。為異源二聚體,其α亞基與促黃體素(LH)、促濾泡素(FSH)和促甲狀腺激素(TSH)的α亞基相同,其β亞基則不同。α亞基含92個胺基酸殘基,β亞基含145個胺基酸殘基。
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