毡毛美洲茶素

毡毛美洲茶素（英语：Velutin）是从Xylosma velutina^[1]和巴西莓果中分离出来的化合物。^[2]它被归类为黄酮。

毡毛美洲茶素
IUPAC名 4′,5-Dihydroxy-3′,7-dimethoxyflavone
系统名 5-Hydroxy-2-(4-hydroxy-3-methoxyphenyl)-7-methoxy-4H-1-benzopyran-4-one
别名	Flavoyadorigenin B
识别
CAS号	25739-41-7  Y
PubChem	5464381
ChemSpider	4576639
SMILES	COC1=CC(=C2C(=C1)OC(=CC2=O)C3=CC(=C(C=C3)O)OC)O
InChI	1/C17H14O6/c1-21-10-6-12(19)17-13(20)8-14(23-16(17)7-10)9-3-4-11(18)15(5-9)22-2/h3-8,18-19H,1-2H3
InChIKey	ROCUOVBWAWAQFD-UHFFFAOYAA
ChEBI	177047
性质
化学式	C17H14O6
摩尔质量	314.29 g·mol−1
若非注明，所有数据均出自标准状态（25 ℃，100 kPa）下。

毡毛美洲茶素具有多种生物活性，例如皮肤美白（抗黑色素生成）作用，以及潜在的抗炎、抗过敏、抗氧化和抗菌活性。^[3]

参考资料

1. Chang, P. T. Otto; Cordell, Geoffrey A.; Fong, Harry H. S.; Farnsworth, Norman R. Velutinic acid, a new friedelane derivative from Xylosma velutina (Flacourtiaceae). Phytochemistry. 1 January 1977, 16 (9): 1443–1445. Bibcode:1977PChem..16.1443C. doi:10.1016/S0031-9422(00)88804-4.
2. Xie, C; Kang, J; Li, Z; Schauss, A. G.; Badger, T. M.; Nagarajan, S; Wu, T; Wu, X. The açaí flavonoid velutin is a potent anti-inflammatory agent: Blockade of LPS-mediated TNF-α and IL-6 production through inhibiting NF-κB activation and MAPK pathway. The Journal of Nutritional Biochemistry. 2012, 23 (9): 1184–91. PMID 22137267. doi:10.1016/j.jnutbio.2011.06.013.
3. Jung, Se-Hui; Heo, Hee-Young; Choe, Jung-Won; Kim, Jaehyun; Lee, Kooyeon. Anti-Melanogenic Properties of Velutin and Its Analogs. Molecules (Basel, Switzerland). 2021-05-19, 26 (10): 3033. ISSN 1420-3049. PMC 8160911 . PMID 34069624. doi:10.3390/molecules26103033 .