IL15RA

IL15RA
已知的结构
PDB	直系同源搜索: PDBe RCSB
PDBID列表
	2ERS、2Z3Q、2Z3R、4GS7
识别号
别名	IL15RA；, CD215, Interleukin 15 receptor, alpha subunit, interleukin 15 receptor subunit alpha
外部ID	OMIM：601070 MGI：104644 HomoloGene：1650 GeneCards：IL15RA
基因位置（人类）
染色体	10号染色体
终止	5,978,187 bp
基因位置（小鼠）
染色体	小鼠2号染色体
终止	11,739,128 bp
RNA表达模式
	查阅更多表达数据
基因本体
分子功能	• cytokine receptor activity; • 血浆蛋白结合; • signal transducer activity; • protein kinase binding; • interleukin-15 receptor activity;
细胞组分	• cytoplasmic vesicle; • integral component of membrane; • 细胞外区域; • Golgi membrane; • 高尔基体; • 核膜; • endoplasmic reticulum membrane; • cytoplasmic vesicle membrane; • 细胞核; • 内质网; • 膜; • 细胞膜; • 细胞外空间; • 核内体; • cell surface;
生物学过程	• 细胞增殖; • 信号转导; • interleukin-15-mediated signaling pathway; • positive regulation of phagocytosis;
	Sources:Amigo / QuickGO
直系同源
	3601
	16169
	ENSG00000134470
	ENSMUSG00000023206
	Q13261
	Q60819
NM_001243539; NM_001256765; NM_002189; NM_172200; NM_001351095;
	NM_001351096; NM_001351097
NM_001271497; NM_001271498; NM_001271499; NM_001271500; NM_001271501;
	NM_008358; NM_133836
NP_001230468; NP_001243694; NP_002180; NP_751950; NP_001338024;
	NP_001338025; NP_001338026
NP_001258426; NP_001258427; NP_001258428; NP_001258429; NP_001258430;
	NP_032384; NP_598597
	维基数据
查看/编辑人类	查看/编辑小鼠

白介素-15受体α亚基（Interleukin-15 receptor subunit alpha，缩写IL15RA）也称为分化簇215（CD215，cluster of differentiation 215）是一种细胞表面蛋白质，由人类基因 IL15RA 编码^[5]，与β亚基（CD122）、γ亚基（CD132）共同组成白介素-15受体^[6]。

事实速览 IL15RA, 已知的结构 ...

关闭

6 sources

参考资料

[1]
GRCh38: Ensembl release 89: ENSG00000134470 - Ensembl, May 2017
[2]
GRCm38: Ensembl release 89: ENSMUSG00000023206 - Ensembl, May 2017
[3]
Human PubMed Reference:. National Center for Biotechnology Information, U.S. National Library of Medicine.
[4]
Mouse PubMed Reference:. National Center for Biotechnology Information, U.S. National Library of Medicine.
[5]
EntrezGene 3601
[6]
Anderson DM, Kumaki S, Ahdieh M, Bertles J, Tometsko M, Loomis A, Giri J, Copeland NG, Gilbert DJ, Jenkins NA. Functional characterization of the human interleukin-15 receptor alpha chain and close linkage of IL15RA and IL2RA genes. J. Biol. Chem. 1995, 270 (50): 29862–9. PMID 8530383. doi:10.1074/jbc.270.50.29862 .

外部链接

医学主题词表（MeSH）：Interleukin-2+Receptors

[refGRCh38Ensembl-1] [1]
GRCh38: Ensembl release 89: ENSG00000134470 - Ensembl, May 2017

[refGRCm38Ensembl-2] [2]
GRCm38: Ensembl release 89: ENSMUSG00000023206 - Ensembl, May 2017

[3] [3]
Human PubMed Reference:. National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] [4]
Mouse PubMed Reference:. National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] [5]
EntrezGene 3601

[pmid8530383-6] [6]
Anderson DM, Kumaki S, Ahdieh M, Bertles J, Tometsko M, Loomis A, Giri J, Copeland NG, Gilbert DJ, Jenkins NA. Functional characterization of the human interleukin-15 receptor alpha chain and close linkage of IL15RA and IL2RA genes. J. Biol. Chem. 1995, 270 (50): 29862–9. PMID 8530383. doi:10.1074/jbc.270.50.29862 .

[5]

[6]

[1]

[2]

[3]

[4]