22Rv1

22Rv1 (亦称CWR-22rv1) 是人类前列腺癌细胞系^[1]，最初是分离自嫁接在小鼠体内，并且在其体内繁殖的CWR22R细胞的异种移植物^[2]^[3]。22Rv1细胞对前列腺特异抗原呈现阳性反应，二羟基睾脂酮轻微刺激着细胞的生长，而表皮生长因子则能刺激细胞生长，但是TGFβ-1（英语：TGF beta 1）不能够抑制细胞增殖^[1]。22Rv1细胞产生高滴度的异嗜性鼠白血病相关病毒（英语：Xenotropic murine leukemia virus-related virus） (XMRV) ^[4] 。

参考资料

[1]
Sramkoski, RM; Pretlow TG, 2nd; Giaconia, JM; Pretlow, TP; Schwartz, S; Sy, MS; Marengo, SR; Rhim, JS; Zhang, D; Jacobberger, JW. A new human prostate carcinoma cell line, 22Rv1.. In vitro cellular & developmental biology. Animal. NaN, 35 (7): 403–9 [2019-12-17]. PMID 10462204. doi:10.1007/s11626-999-0115-4. （原始内容存档于2019-12-17）. 请检查|date=中的日期值 (帮助)
[2]
Woods-Burnham, L; Basu, A; Cajigas-Du Ross, CK; Love, A; Yates, C; De Leon, M; Roy, S; Casiano, CA. The 22Rv1 prostate cancer cell line carries mixed genetic ancestry: Implications for prostate cancer health disparities research using pre-clinical models.. The Prostate. 2017-12, 77 (16): 1601–1608 [2019-12-17]. PMID 29030865. doi:10.1002/pros.23437.
[3]
Pretlow, TG; Wolman, SR; Micale, MA; Pelley, RJ; Kursh, ED; Resnick, MI; Bodner, DR; Jacobberger, JW; Delmoro, CM; Giaconia, JM. Xenografts of primary human prostatic carcinoma.. Journal of the National Cancer Institute. 1993-03-03, 85 (5): 394–8 [2019-12-17]. PMID 8433392. doi:10.1093/jnci/85.5.394. （原始内容存档于2019-12-17）.
[4]
Yang, J; Battacharya, P; Singhal, R; Kandel, ES. Xenotropic murine leukemia virus-related virus (XMRV) in prostate cancer cells likely represents a laboratory artifact.. Oncotarget. 2011-05, 2 (5): 358–62 [2019-12-17]. PMID 21642749. doi:10.18632/oncotarget.287. （原始内容存档于2019-12-17）.