17α-羟孕烯醇酮(英语:17α-Hydroxypregnenolone)是一种孕烷类(C21)甾体物质,由孕烯醇酮在C17的α位羟基化而来。体内的17α-羟孕烯醇酮由肾上腺和生殖腺的线粒体细胞色素P450氧化酶——17α-羟化酶(CYP17A1)氧化而来。人类体内的17α-羟孕烯醇酮在青春期末达到高峰,随后下降[1],在孕期也有较高浓度。
药物动力学数据 | |
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药物代谢 | Adrenal, Gonads |
识别信息 | |
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CAS号 | 387-79-1 |
PubChem CID | |
ChemSpider | |
ChEBI | |
CompTox Dashboard (EPA) | |
ECHA InfoCard | 100.006.239 |
化学信息 | |
化学式 | C21H32O3 |
摩尔质量 | 332.48 g/mol |
3D模型(JSmol) | |
熔点 | 268 °C(514 °F) |
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另见
参考文献
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