1-氯-3-溴丙烷

1-氯-3-溴丙烷是一种有机卤化物，化学式为BrCH₂CH₂CH₂Cl。它是无色的液体，由烯丙基氯和溴化氢的自由基加成反应制得。^[4]

H₂C=CHCH₂Cl + HBr —^(PhCO₂)₂→ BrCH₂CH₂CH₂Cl

1-氯-3-溴丙烷
别名	1-溴-3-氯丙烷
识别
CAS号	109-70-6  Y
PubChem	8006
ChemSpider	7715
SMILES	C(CCl)CBr
UN编号	2688
RTECS	TX4113000
性质
化学式	C3H6BrCl
摩尔质量	157.44 g·mol−1
外观	无色液体
密度	1.5222 g·cm−3（20 °C）[1]
熔点	−58.90 °C（214.25 K）[2]
沸点	143.3 °C（416.4 K）[3]
危险性
GHS危险性符号
GHS提示词	警告
H-术语	H226, H302, H315, H319, H331, H332, H335, H341, H412
P-术语	P201, P202, P210, P233, P240, P241, P242, P243, P261, P264, P270, P271, P273, P280
若非注明，所有数据均出自标准状态（25 ℃，100 kPa）下。

它是一种烷基化试剂，可以用于引入ClCH₂CH₂CH₂-^[5]或-CH₂CH₂CH₂-基团。^[6]

参考文献

1. Afanas'ev, I. B.; Beer, A. A. Telomerization of bromochloromethane with ethylene. Zhurnal Vsesoyuznogo Khimicheskogo Obshchestva im. D. I. Mendeleeva, 1962. 7: 595-597. ISSN: 0373-0247.
2. "Hazardous Substances Data Bank" data were obtained from the National Library of Medicine (US). Retrieved from SciFinder. [2019-9-6]
3. Cash, Gordon G.; Hartigan, Suzanne; Tunkel, Jay. Normal boiling points of haloalkanes from electrotopological state indices. Toxicological & Environmental Chemistry. 2008, 90 (6): 1073–1089. ISSN 0277-2248. doi:10.1080/02772240701862116.
4. Dagani, M. J.; Barda, H. J.; Benya, T. J.; Sanders, D. C., Bromine Compounds, Ullmann's Encyclopedia of Industrial Chemistry, Weinheim: Wiley-VCH, 2005, doi:10.1002/14356007.a04_405
5. Evans, D. A.; Domeier, L. A. Endocyclic Enamine Synthesis: N-Methyl-2-Phenyl-δ2-tetrahydropyridine. Org. Synth. 1974, 54: 93. doi:10.15227/orgsyn.054.0093.
6. Glass, D. B.; Weissberger, A. Julolidine. Org. Synth. 1946, 26: 40. doi:10.15227/orgsyn.026.0040.