同源框
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同源(异形)框(英语:Homeobox),或称“同源匣”是某些影响动物、真菌及植物发育的基因所拥有的一段DNA序列,拥有同源框的基因称作同源异形基因,统称同源异形基因家族。
Quick Facts Homeodomain, 鉴定 ...
Homeodomain | |||||||||||
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The Antennapedia homeodomain protein from Drosophila melanogaster bound to a fragment of DNA.[1] The recognition helix and unstructured N-terminus are bound in the major and minor grooves respectively. | |||||||||||
鉴定 | |||||||||||
标志 | 同源框结构域(Homeodomain) | ||||||||||
Pfam | PF00046(旧版) | ||||||||||
Pfam宗系 | CL0123(旧版) | ||||||||||
InterPro(英语:InterPro) | IPR001356 | ||||||||||
SMART(英语:Simple Modular Architecture Research Tool) | SM00389 | ||||||||||
PROSITE(英语:PROSITE) | PDOC00027 | ||||||||||
SCOP(英语:Structural Classification of Proteins) | 1ahd / SUPFAM | ||||||||||
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这段序列之长度约180个核苷酸,能转录出一段蛋白质结构域,称为同源框结构域。
参考文献
- PDB 1AHD; Billeter M, Qian YQ, Otting G, Müller M, Gehring W, Wüthrich K. Determination of the nuclear magnetic resonance solution structure of an Antennapedia homeodomain-DNA complex. Journal of Molecular Biology. Dec 1993, 234 (4): 1084–93. PMID 7903398. doi:10.1006/jmbi.1993.1661.