鉀離子通道開放劑

鉀離子通道開放劑(英文：Potassium channel opener)是一種促進離子通過鉀離子通道傳輸的藥物。

例子

一些示例包括：

• 二氮嗪^[1]
• 米諾地爾^[2]
• 尼可地爾^[3]
• 吡那地爾^[4]
• 瑞替加濱,^[5][6]
• 氟吡汀

參見

• 鉀離子通道阻斷劑

參考資料

1. Mizutani S, Prasad SM, Sellitto AD, Schuessler RB, Damiano RJ, Lawton JS. Myocyte volume and function in response to osmotic stress: observations in the presence of an adenosine triphosphate-sensitive potassium channel opener. Circulation. August 2005, 112 (9 Suppl): I219–23. PMID 16159820. doi:10.1161/CIRCULATIONAHA.104.523746 (不活躍 2021-01-14).
2. Wang T. The effects of the potassium channel opener minoxidil on renal electrolytes transport in the loop of henle. J. Pharmacol. Exp. Ther. February 2003, 304 (2): 833–40. PMID 12538840. S2CID 6948410. doi:10.1124/jpet.102.043380.
3. Sudo H, Yogo K, Ishizuka N, Otsuka H, Horie S, Saito K. Nicorandil, a potassium channel opener and nitric oxide donor, improves the frequent urination without changing the blood pressure in rats with partial bladder outlet obstruction. Biol. Pharm. Bull. November 2008, 31 (11): 2079–82. PMID 18981577. doi:10.1248/bpb.31.2079 .
4. Stojnic N, Gojkovic-Bukarica L, Peric M, et al. Potassium channel opener pinacidil induces relaxation of the isolated human radial artery. J. Pharmacol. Sci. June 2007, 104 (2): 122–9. PMID 17538231. doi:10.1254/jphs.FP0061434 . ^{[失效連結]}
5. Rundfeldt C. The new anticonvulsant retigabine (D-23129) acts as an opener of K+ channels in neuronal cells. European Journal of Pharmacology. October 1997, 336 (2–3): 243–9. PMID 9384239. doi:10.1016/S0014-2999(97)01249-1.
6. Main MJ, Cryan JE, Dupere JR, Cox B, Clare JJ, Burbidge SA. Modulation of KCNQ2/3 potassium channels by the novel anticonvulsant retigabine. Molecular Pharmacology. August 2000, 58 (2): 253–62. PMID 10908292. doi:10.1124/mol.58.2.253.