約在公元前155年之後,月氏再次被烏孫和匈奴聯盟所擊敗,被迫再向南移動,而又再次驅散斯基泰人,後者向南遷移至巴克特里亞和今日的阿富汗,並向西南方向的帕提亞接近。公元前145年左右,塞迦人似乎已進入希臘-巴克特里亞王國的領土,他們在那裏把希臘城市埃康農(英語:Alexandria on the Oxus)焚為為平地。(請參閱希臘-巴克特里亞王國#滅亡)月氏留在阿姆河北岸的粟特,但正如中國漢朝使者張騫在公元前126年訪問該地區時所描述,他們成為巴克特里亞地區塞迦人的宗主國。[29]
印度-斯基泰人在印度被稱為「Shaka」,是波斯人的Saka的擴展名。從《摩訶婆羅多》戰爭時期(大約在公元前3100年,在鬥爭時(印度教中四個宇迦循環中的最後一個)開始之前)[56])發生時,Shakas在文本中被提及無數次,如往世書、摩奴法論、羅摩衍那、摩訶婆羅多、大疏(Mahabhasiya of Patanjali)、伐羅訶密希羅的Brhat Samhita、Kavyamimamsa、Brihat-Katha-Manjari、故事海,和其他一些古文本。它們被描述為西北部好戰部落中的一支。
入侵印度並建立多個王國的斯基泰人部族,除塞迦人以外,還包括其他同盟部落,例如米底人、大益、和馬薩革泰人。這些部族的人後來全部被印度主流社會的剎帝利社群所吸收。[63]
Shakas從前是居住在跨赫莫多斯(英語:Hemodos)地區的人們,即往世書中提到的Shakadvipa,或是古典著作中提到的Scythia。查拉克斯的伊西多(英語:Isidor of Charax)(公元1世紀初)中、證明這些人居住在Sakastana(現代錫斯坦)。愛利脫利亞海周航記(約公元70-80年)也證明居住在印度河下游的明納加拉是斯基泰人。托勒密(約公元140年)還證明居住在印度西南部,包括帕塔林(英語:Patalene)和索拉什特拉地區的是印度-斯基泰人。
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