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腔室症候群是對肢體、生命產生威脅的一種狀況,是由於身體某部位神經、血管及肌肉在一個封閉的空間(腔室)中受到壓迫[1]。起因於腔室中升高的壓力,造成血管灌流不足,導致組織缺氧而壞死。腔室症候群最常發生在前臂及小腿,[2] 並可分成急性、亞急性及慢性腔室症候群。根據蘭金(Rankin, 1981)的定義,腔室症候群的起因是一個密閉空間中的壓力,使得該空間的循環及組織功能的受到阻礙。
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因為組成腔室的結締組織延展性降低使得流經該腔室的血流量減少,或是由於腔室中肌肉的腫脹造成腔室中壓力的劇烈升高。常造成腔室症候群的原因包括脛骨或前臂骨折,由於組織的傷害、出血、血管穿刺、靜脈藥物注射,長時間固定、肢體的壓迫,粉碎性的傷害及燒燙傷造成的再灌注性損傷。[3][4] 另一個可能的原因是由於服用肌氨酸,有研究指出服用肌氨酸的病史與腔室症候群有一定關係。[5][6]
存档副本. [2011-12-28]. (原始內容存檔於2011-09-04).
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