小核RNA(英語:small nuclear RNA,常見縮寫snRNA,也見譯為核內小RNA),是含有100到300鹼基RNA

它參與真核生物細胞核RNA的加工。snRNA和許多蛋白質結合在一起成為小胞核核糖核蛋白snRNPssmall nuclear ribonucleoproteins),參與信使RNA前體(pre-mRNA)的剪接,使後者成為成熟mRNA

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