甲二胺是最簡單的二胺,化學式CH2(NH2)2。雖然甲二胺本身只能在溶液中短暫存在,[2]但它的鹽酸鹽早在1914年就用於化學合成,[3]能簡單方便地把氨基酸轉化成酰胺。[4]
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在類似星際空間的環境,甲胺與氨暴露於高能電子下會發生反應,生成甲二胺。[2]由於甲二胺結構簡單,且含有N-C-N鍵,因此它可能是生命起源中,同樣具有N-C-N鍵的雜環化合物(如核鹼基)的重要中間體。[2]
Watrous, Alexandria G; Westbrook, Brent R; Fortenberry, Ryan C. On the detectability of interstellar diaminomethane ((NH2)2CH2). Monthly Notices of the Royal Astronomical Society. 2023-12-23, 527 (4): 11090–11094. ISSN 0035-8711. doi:10.1093/mnras/stad3938.
Galaverna, Gianni; Corradini, Roberto; Dossena, Arnaldo; Marchelli, Rosangela. Diaminomethane dihydrochloride, a novel reagent for the synthesis of primary amides of amino acids and peptides from active esters. International Journal of Peptide and Protein Research. 1993, 42 (1): 53–57. ISSN 0367-8377. doi:10.1111/j.1399-3011.1993.tb00349.x.