JWH-200,也稱作WIN 55,225[1],是一種由約翰·威廉·霍夫曼小組合成的萘甲酰基吲哚類JWH大麻素[2],分子式C25H24N2O2,可作為鎮痛藥使用。
Quick Facts 臨床資料, 其他名稱 ...
JWH-200![Thumb](//upload.wikimedia.org/wikipedia/commons/thumb/f/fc/JWH-200.svg/180px-JWH-200.svg.png) |
|
其他名稱 | WIN 55,225 |
---|
|
法律規範 |
|
---|
|
(1-(2-Morpholin-4-ylethyl)indol-3-yl)-naphthalen-1-ylmethanone
|
CAS號 | 103610-04-4 Y |
---|
PubChem CID | |
---|
ChemSpider | |
---|
UNII | |
---|
CompTox Dashboard (EPA) | |
---|
|
化學式 | C25H24N2O2 |
---|
摩爾質量 | 384.48 g·mol−1 |
---|
3D模型(JSmol) | |
---|
O=C(C1=CC=CC2=C1C=CC=C2)C3=CN(C4=C3C=CC=C4)CCN5CCOCC5
|
InChI=1S/C25H24N2O2/c28-25(22-10-5-7-19-6-1-2-8-20(19)22)23-18-27(24-11-4-3-9-21(23)24)13-12-26-14-16-29-17-15-26/h1-11,18H,12-17H2 Key:SZWYXJHTNGJPKU-UHFFFAOYSA-N
|
Close
Dutta AK, Ryan W, Thomas BF, Singer M, Compton DR, Martin BR, Razdan RK. Synthesis, pharmacology, and molecular modeling of novel 4-alkyloxy indole derivatives related to cannabimimetic aminoalkyl indoles (AAIs). Bioorganic & Medicinal Chemistry. August 1997, 5 (8): 1591–600. PMID 9313864. doi:10.1016/S0968-0896(97)00111-9.
Huffman JW, Mabon R, Wu MJ, Lu J, Hart R, Hurst DP, Reggio PH, Wiley JL, Martin BR. 3-Indolyl-1-naphthylmethanes: new cannabimimetic indoles provide evidence for aromatic stacking interactions with the CB(1) cannabinoid receptor. Bioorganic & Medicinal Chemistry. February 2003, 11 (4): 539–49. PMID 12538019. S2CID 29107765. doi:10.1016/S0968-0896(02)00451-0.