洛森重排反應Lossen重排反應)中,異羥肟酸1先與失水劑(如對甲苯磺酰氯)反應得到O-取代的中間體2,然後重排生成異氰酸酯3[1][2]

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Lossen重排反應

異羥肟酸一般由相應的羥胺反應製備。[3]該反應的綜述參見:[4][5][6]

參考資料

  1. ^ Lossen, W. Ann. 1872, 161, 347.
  2. ^ Lossen, W. Ann. 1874, 175, 271 & 313.
  3. ^ Yale, H. L. Chem. Rev. 1943, 33, 209. (Review)
  4. ^ Bauer, L.; Exner, O. Angew. Chem. Int. Ed. Engl. 1974, 13, 376. (Review)
  5. ^ Shiori, T. Comp. Org. Syn. 1991, 6, 821-825. (Review)
  6. ^ Hauser, C. R.; Renfrow, Jr., W. B. Organic Syntheses, Coll. Vol. 2, p.67 (1943); Vol. 19, p.15 (1939). (Article頁面存檔備份,存於互聯網檔案館))

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