催產素酶（Oxytocinase）是一種可以代謝催產素的酶[1]。最著名的催產素酶是Leucyl-cystinyl氨肽酶[1][2]，本身也是腦啡肽酶，已知也有其他的催產素酶[1][3]。懷孕時，催產素酶可以平衡催產素的濃度，因為隨著胎兒成長，胎兒分泌的催產素會增加，催產素酶會分解胎兒分泌的催產素，以維持平衡[2]。有研究發現催產素酶的濃度會隨胎齡漸漸增加，直到分娩為止，因此胎兒的發育可以用催產素酶濃度進行評估[4]。
阿嗎他定、短整合蛋白（ubenimex）及嘌呤黴素都可以抑制催產素的代謝，不過他們也會抑制其他多肽（像是後葉加壓素、甲硫腦素及強啡肽等）的分解，[5][3][6]。EDTA、L-甲硫氨酸、鄰二氮菲及磷酸阿米酮也會抑制催產素的代謝[7]。
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