貝格曼降解反應（德語：Bergmann-Abbau），又稱貝格曼遞降反應，是去除肽C-端氨基酸的方法。[1][2]
首先製得相應的酰基疊氮(1)，然後酰基疊氮在苄醇存在下經庫爾提斯重排反應，得到少一個碳的胺的苄氧羰基取代物(3)。它經過氫解，即得伯酰胺(4)和醛(5)。
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參考資料
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