肟V

肟V是一种有机化合物，有着用作甜味剂（英语：sweetener）的潜力。它最初于作为人造甜味剂紫苏葶（英语：perillartine）的类似物1976年被报道。^[1]它的甜度约为蔗糖的450倍，且比紫苏葶更易溶于水。^[2]目前已有肟V的代谢和毒理学研究，^[3]但它并未上市。

肟V
IUPAC名 4-(Methoxymethyl)-1,4-cyclohexadiene-1-carboxaldehyde syn-oxime
识别
CAS号	59691-20-2
PubChem	9577332
SMILES	C(=N/O)\C=1CC=C(COC)CC1
InChI	1S/C9H13NO2/c1-12-7-9-4-2-8(3-5-9)6-10-11/h2,5-6,11H,3-4,7H2,1H3/b10-6+
InChIKey	LNTHQBNSXNQPPZ-UXBLZVDNSA-N
性质
化学式	C9H13NO2
摩尔质量	167.21 g·mol−1
若非注明，所有数据均出自标准状态（25 ℃，100 kPa）下。

它存在于柑橘属中。^[4][5]

参考文献

1. Acton, E. M.; Stone, H. Potential New Artificial Sweetener from Study of Structure-Taste Relationships. Science. 1976, 193 (4253): 584–586. Bibcode:1976Sci...193..584A. PMID 959816. doi:10.1126/science.959816.
2. A. Douglas Kinghorn and Cesar M. Comadre. Chapter 12. Less Common High-Potency Sweeteners. Lyn O'Brien-Nabors (编). Alternative Sweeteners 3rd. 2001: 222. ISBN 0-8247-0437-1.
3. Hitoma, C.; Acton, E. M.; Degraw, J. I.; Thomas, D. W. Metabolic and Toxicologic Study of an Artificial Sweetener, Oxime V. Drug and Chemical Toxicology. 1985, 8 (4): 195–206. PMID 3841048. doi:10.3109/01480548509038645.
4. Wang, Zhixin; Gmitter, Frederick G.; Grosser, Jude W.; Wang, Yu. Natural Sweeteners and Sweetness-Enhancing Compounds Identified in Citrus Using an Efficient Metabolomics-Based Screening Strategy. Journal of Agricultural and Food Chemistry. 2022, 70 (34): 10593–10603. PMID 35980814. S2CID 251645690. doi:10.1021/acs.jafc.2c03515.
5. Researchers find new sugar substitutes in citrus that could change food and beverage industry. Science Daily. September 20, 2022 [2022-09-23]. （原始内容存档于2022-09-28）.