2,4,5-三羟基甲基苯丙胺

2,4,5-三羟基甲基苯丙胺（英语：2,4,5-Trihydroxymethamphetamine，缩写THMA）是一种神经毒素，分子式C₁₀H₁₅NO₃，也是MDMA（3,4-亚甲二氧甲基苯丙胺）在体内的代谢产物^[1][2]。

2,4,5-三羟基甲基苯丙胺
IUPAC名 5-[2-(Methylamino)propyl]benzene-1,2,4-triol
识别
CAS号	136706-32-6
PubChem	131985
ChemSpider	19983112
SMILES	CNC(C)CC1=C(O)C=C(O)C(O)=C1
性质
化学式	C10H15NO3
摩尔质量	197.23 g·mol−1
若非注明，所有数据均出自标准状态（25 ℃，100 kPa）下。

另见

• 2,4,5-三羟基安非他命

参考文献

1. Ikram Elayan; James W. Gibb; Glen R. Hanson; Rodger L. Foltza; Heng Keang Lima; Michel Johnson. Long-term alteration in the central monoaminergic systems of the rat by 2,4,5-trihydroxyamphetamine but not by 2-hydroxy-4,5-methylenedioxymethamphetamine or2-hydroxy-4,5-methylenedioxyamphetamine. European Journal of Pharmacology. 1992, 221 (2–3): 281–288. PMID 1358654. doi:10.1016/0014-2999(92)90714-F.
2. Anne Neudörffer; Melanie Mueller; Claire-Marie Martinez; Annis Mechan; Una McCann; George A. Ricaurte; Martine Largeron. Synthesis and Neurotoxicity Profile of 2,4,5-Trihydroxymethamphetamine and its 6-(N-Acetylcystein-S-yl) Conjugate. Chem Res Toxicol. 2011, 24 (6): 968–978. PMC 3124246 . PMID 21557581. doi:10.1021/tx2001459.

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