芪类化合物

芪（qí）类化合物（英语：Stilbenoid）是一类有机化合物，带有二苯基乙烯的C₆–C₂–C₆结构^[1][2]，通常由植物合成^[2][3]。

白藜芦醇，生物治疗中最常见的芪类化合物

类型

羟基芪类

化合物	系统名	分子式	CAS号	结构
乙烯雌酚 Stilbestrol	4,4'-二羟基芪 4,4'-dihydroxystilbene	C14H12O2	659-22-3
赤松素 Pinosylvin	3,5-二羟基芪 3,5-dihydroxystilbene	C14H12O2	22139-77-1
3,4'-二羟基二苯乙烯	3,4'-二羟基芪 3,4'-dihydroxystilbene	C14H12O2	62574-04-3
白藜芦醇 Resveratrol	3,5,4'-三羟基芪 3,5,4′-Trihydroxystilbene	C14H12O3	501-36-0
氧化白藜芦醇 Oxyresveratrol	2,4,3',5'-四羟基芪 2,3',4,5'-Tetrahydroxystilbene	C14H12O4	29700-22-9
白皮杉醇 Piceatannol	3,5,3',4'-四羟基芪 3',4',3,5-Tetrahydroxystilbene	C14H12O4	10083-24-6
买麻藤醇 Gnetol	2,6,3',5'-四羟基芪 2,3',4',6-Tetrahydroxystilbene	C14H12O4	86361-55-9

O-甲基化芪类

化合物	系统名	分子式	CAS号	结构
松芪 Pinostilbene	3,4'-二羟基-5-甲氧基芪 3,4'-dihydroxy-5-methoxystilbene	C15H14O3	42438-89-1
4-甲氧基白藜芦醇 4-Methoxyresveratrol	3,5-二羟基-4'-甲氧基芪 3,5-dihydroxy-4'-methoxystilbene	C15H14O3	33626-08-3
丹叶大黄素 Rhapontigenin	3,5,3'-三羟基-4'-甲氧基芪 3,3',5-trihydroxy-4'-methoxystilbene	C15H14O4	500-65-2
异丹叶大黄素 Isorhapontigenin	3,5,4'-三羟基-3'-甲氧基芪 3,4',5-trihydroxy-3'-methoxystilbene	C15H14O4	32507-66-7
闭苞素D Gnetucleistol D	3,5,4'-三羟基-2'-甲氧基芪 3,4',5-trihydroxy-2'-methoxystilbene	C15H14O4	629643-26-1
光茴香脑 Photoanethole	4,4'-二甲氧基芪 4,4′-Dimethoxystilbene	C16H16O2	15638-14-9
紫檀芪 Pterostilbene	3',5'-二甲氧基-4-羟基芪 3',5'-Dimethoxy-4-hydroxystilbene	C16H16O3	537-42-8
3'-羟基紫檀芪 3'-Hydroxypterostilbene	3',5'-二甲氧基-3,4-二羟基芪 3',5'-Dimethoxy-3,4-dihydroxystilbene	C16H16O4	475231-21-1
闭苞素E Gnetucleistol E	3',4'-二甲氧基-3,5-二羟基芪 3',4'-Dimethoxy-3,5-dihydroxystilbene	C16H16O4	629643-27-2

糖苷

化合物	别名	分子式	CAS号	结构
白皮杉醇葡萄糖苷 Astringin	白皮杉醇-3-β-葡萄糖苷	C20H22O9	29884-49-9
曲札芪苷 Quzhaqigan	白皮杉醇-3'-O-葡萄糖苷	C20H22O9	94356-26-0
云杉新苷 Piceid	白藜芦醇-3-β-葡萄糖苷	C20H22O8	27208-80-6
白藜芦醇-4'-O-葡萄糖苷（英语：Resveratroloside） Resveratroloside	白藜芦醇-4'-O-葡萄糖苷	C20H22O8	38963-95-0
异土大黄苷 Isorhapontin	异丹叶大黄素-3-O-β-D-葡萄糖苷	C21H24O9	32727-29-0
土大黄苷 Rhapontin	丹叶大黄素-3-O-β-D-葡萄糖苷	C21H24O9	155-58-8

其它

化合物	别名	分子式	CAS号	结构
八仙花酸 Hydrangeic acid	3,4'-二羟基-2-羧基芪	C15H12O4	491-79-2
苯烯莫德 benvitimod	3,5-二羟基-4-异丙基芪	C17H18O2	79338-84-4
六硝基芪 HNS	2,2′,4,4′,6,6′-六硝基芪	C14H6N6O12	20062-22-0

参考文献

1. V. S. Sobolev; B. W. Horn; T. L. Potter; S. T. Deyrup; J. B. Gloer. Production of Stilbenoids and Phenolic Acids by the Peanut Plant at Early Stages of Growth. J. Agric. Food Chem. 2006, 54 (10): 3505–3511. PMID 19127717. doi:10.1021/jf0602673.
2. Valletta, Alessio; Iozia, Lorenzo Maria; Leonelli, Francesca. Impact of Environmental Factors on Stilbene Biosynthesis. Plants. January 2021, 10 (1): 90. PMC 7823792 . PMID 33406721. doi:10.3390/plants10010090  （英语）.
3. Dubrovina, A. S.; Kiselev, K. V. Regulation of stilbene biosynthesis in plants. Planta. October 2017, 246 (4): 597–623. ISSN 0032-0935. PMID 28685295. S2CID 4015467. doi:10.1007/s00425-017-2730-8 （英语）.