LL-100
维基百科,自由的 encyclopedia
LL-100是100种人类淋巴瘤(Lymphoma)与白血病(Leukemia)细胞系的列表[1],用于药物筛选等许多生物医学研究[2]。
细胞系
Pre-B-ALL
More information 细胞系, 性别 ...
细胞系 | 性别 | 年龄 | 文献 | 外部链接 |
---|---|---|---|---|
697 | 男 | 12Y | [3] | CVCL_0079 (页面存档备份,存于互联网档案馆) |
KOPN-8 | 女 | 3M | [4] | CVCL_1866 (页面存档备份,存于互联网档案馆) |
NALM-6 | 男 | 19Y | [5] | CVCL_0092 (页面存档备份,存于互联网档案馆) |
REH | 女 | 15Y | [6] | CVCL_1650 (页面存档备份,存于互联网档案馆) |
SEM | 女 | 5Y | [7] | CVCL_0095 (页面存档备份,存于互联网档案馆) |
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B-NHL:伯基特淋巴瘤/B-ALL
More information 细胞系, 性别 ...
细胞系 | 性别 | 年龄 | 文献 | 外部链接 |
---|---|---|---|---|
BJAB | 女 | 5Y | [8] | CVCL_5711 (页面存档备份,存于互联网档案馆) |
Daudi | 男 | 16Y | [9] | CVCL_0008 (页面存档备份,存于互联网档案馆) |
Raji | 男 | 11Y | [10] | CVCL_0511 (页面存档备份,存于互联网档案馆) |
Ramos | 男 | 3Y | [11] | CVCL_0597 (页面存档备份,存于互联网档案馆) |
VAL | 女 | 50Y | [12] | CVCL_1819 (页面存档备份,存于互联网档案馆) |
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B-NHL: 慢性淋巴细胞白血病/PLL
More information 细胞系, 性别 ...
细胞系 | 性别 | 年龄 | 文献 | 外部链接 |
---|---|---|---|---|
HG-3 | 男 | 70Y | [13] | CVCL_Y547 (页面存档备份,存于互联网档案馆) |
JVM-3 | 男 | 73Y | [14] | CVCL_1320 (页面存档备份,存于互联网档案馆) |
JVM-13 | 男 | 60-69Y | [15] | CVCL_1318 (页面存档备份,存于互联网档案馆) |
MEC-1 | 男 | 61Y | [16] | CVCL_1870 (页面存档备份,存于互联网档案馆) |
PGA-1 | 男 | 未知 | [17] | CVCL_Y545 (页面存档备份,存于互联网档案馆) |
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B-NHL: DLBCL ABC
More information 细胞系, 性别 ...
细胞系 | 性别 | 年龄 | 文献 | 外部链接 |
---|---|---|---|---|
NU-DHL-1 | 男 | 73Y | [18] | CVCL_1876 (页面存档备份,存于互联网档案馆) |
OCI-Ly3 | 男 | 52Y | [19] | CVCL_8800 (页面存档备份,存于互联网档案馆) |
Ri-1 | 女 | 57Y | [20] | CVCL_1885 (页面存档备份,存于互联网档案馆) |
U-2932 | 女 | 29Y | [21] | CVCL_1896 (页面存档备份,存于互联网档案馆) |
U-2946 | 男 | 52Y | [22] | CVCL_X503[失效链接] |
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B-NHL: DLBCL GC
More information Cell line, 性别 ...
Cell line | 性别 | 年龄 | 文献 | 外部链接 |
---|---|---|---|---|
DoHH2 | 男 | 60Y | [23] | CVCL_1179 (页面存档备份,存于互联网档案馆) |
OCI-Ly7 | 男 | 48Y | [19] | CVCL_1881[失效链接] |
OCI-Ly19 | 女 | 27Y | [24] | CVCL_1878 (页面存档备份,存于互联网档案馆) |
SU-DHL-4 | 男 | 38Y | [25] | CVCL_0539 (页面存档备份,存于互联网档案馆) |
SU-DHL-6 | 男 | 43Y | [25] | CVCL_2206 (页面存档备份,存于互联网档案馆) |
WSU-DLCL2 | 男 | 41Y | [26] | CVCL_1902 (页面存档备份,存于互联网档案馆) |
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B-NHL: 毛细胞白血病
More information 细胞系, 性别 ...
细胞系 | 性别 | 年龄 | 文献 | 外部链接 |
---|---|---|---|---|
BONNA-12 | 男 | 46Y | [27] | CVCL_1090 (页面存档备份,存于互联网档案馆) |
Hair-M | 男 | 86Y | [28] | CVCL_B401 (页面存档备份,存于互联网档案馆) |
HC-1 | 男 | 56Y | [29] | CVCL_1243 (页面存档备份,存于互联网档案馆) |
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B-NHL: 被套细胞淋巴瘤
More information 细胞系, 性别 ...
细胞系 | 性别 | 年龄 | 文献 | 外部链接 |
---|---|---|---|---|
Granta-519 | 女 | 58Y | [30] | CVCL_1818 (页面存档备份,存于互联网档案馆) |
JeKo-1 | 女 | 78Y | [31] | CVCL_1865 (页面存档备份,存于互联网档案馆) |
JVM-2 | 女 | 63Y | [14] | CVCL_1319 (页面存档备份,存于互联网档案馆) |
Mino | 男 | 68Y | [32] | CVCL_1872 (页面存档备份,存于互联网档案馆) |
REC-1 | 男 | 61Y | [33] | CVCL_1884 (页面存档备份,存于互联网档案馆) |
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B-NHL: PEL
More information 细胞系, 性别 ...
细胞系 | 性别 | 年龄 | 文献 | 外部链接 |
---|---|---|---|---|
BC-3 | 男 | 85Y | [34] | CVCL_1080 (页面存档备份,存于互联网档案馆) |
BCBL-1 | 男 | 40Y | [35] | CVCL_0165 (页面存档备份,存于互联网档案馆) |
CRO-AP2 | 男 | 49Y | [36] | CVCL_1147 (页面存档备份,存于互联网档案馆) |
CRO-AP5 | 男 | 35Y | [37] | CVCL_1148 (页面存档备份,存于互联网档案馆) |
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B-NHL: PMBL
多发性骨髓瘤/PCL
More information 细胞系, 性别 ...
细胞系 | 性别 | 年龄 | 文献 | 外部链接 |
---|---|---|---|---|
KMS-12-BM | 女 | 64Y | [39] | CVCL_1334 (页面存档备份,存于互联网档案馆) |
L-363 | 女 | 36Y | [40] | CVCL_1357 (页面存档备份,存于互联网档案馆) |
LP-1 | 女 | 56Y | [41] | CVCL_0012 (页面存档备份,存于互联网档案馆) |
OPM-2 | 女 | 56Y | [42] | CVCL_1625 (页面存档备份,存于互联网档案馆) |
RPMI-8226 | 男 | 61Y | [43] | CVCL_0014 (页面存档备份,存于互联网档案馆) |
U-266 | 男 | 53Y | [44] | CVCL_0566 (页面存档备份,存于互联网档案馆) |
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More information 细胞系, 性别 ...
细胞系 | 性别 | 年龄 | 文献 | 外部链接 |
---|---|---|---|---|
HDLM-2 | 男 | 74Y | [45] | CVCL_0009 (页面存档备份,存于互联网档案馆) |
KM-H2 | 男 | 37Y | [46] | CVCL_1330 (页面存档备份,存于互联网档案馆) |
L-428 | 女 | 37Y | [45] | CVCL_1361 (页面存档备份,存于互联网档案馆) |
L-1236 | 男 | 34Y | [47] | CVCL_2096 (页面存档备份,存于互联网档案馆) |
SUP-HD1 | 男 | 37Y | [48] | CVCL_2208 (页面存档备份,存于互联网档案馆) |
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T-ALL/T-LL
More information 细胞系, 性别 ...
细胞系 | 性别 | 年龄 | 文献 | 外部链接 |
---|---|---|---|---|
CCRF-CEM | 女 | 3Y11M | [49] | CVCL_0207 (页面存档备份,存于互联网档案馆) |
DND-41 | 男 | 13Y | [50] | CVCL_2022 (页面存档备份,存于互联网档案馆) |
HPB-ALL | 男 | 14Y | [51] | CVCL_1820 (页面存档备份,存于互联网档案馆) |
Jurkat | 男 | 14Y | [52] | CVCL_0065 (页面存档备份,存于互联网档案馆) |
MOLT-4 | 男 | 19Y | [53] | CVCL_0013 (页面存档备份,存于互联网档案馆) |
RPMI-8402 | 女 | 16Y | [54] | CVCL_1667 (页面存档备份,存于互联网档案馆) |
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Mature T-Malignancy
More information 细胞系, 性别 ...
细胞系 | 性别 | 年龄 | 文献 | 外部链接 |
---|---|---|---|---|
DERL-7 | 男 | 30Y | [55] | CVCL_2017 (页面存档备份,存于互联网档案馆) |
HH | 男 | 61Y | [56] | CVCL_1280 (页面存档备份,存于互联网档案馆) |
MOTN-1 | 女 | 65Y | [57] | CVCL_2127 (页面存档备份,存于互联网档案馆) |
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NK Malignancy
More information 细胞系, 性别 ...
细胞系 | 性别 | 年龄 | 文献 | 外部链接 |
---|---|---|---|---|
KHYG-1 | 女 | 45Y | [58] | CVCL_2976 (页面存档备份,存于互联网档案馆) |
NK-92 | 男 | 50Y | [59] | CVCL_2142 (页面存档备份,存于互联网档案馆) |
YT | 男 | 15Y | [60] | CVCL_1797 (页面存档备份,存于互联网档案馆) |
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间变性大细胞淋巴瘤
More information 细胞系, 性别 ...
细胞系 | 性别 | 年龄 | 文献 | 外部链接 |
---|---|---|---|---|
DEL | 男 | 12Y | [61] | CVCL_1170 (页面存档备份,存于互联网档案馆) |
SR-786 | 男 | 11Y | [62] | CVCL_1711 (页面存档备份,存于互联网档案馆) |
SU-DHL-1 | 男 | 10Y | [63] | CVCL_0538 (页面存档备份,存于互联网档案馆) |
SUP-M2 | 女 | 5Y | [64] | CVCL_2209 (页面存档备份,存于互联网档案馆) |
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AML myelocytic
More information 细胞系, 性别 ...
细胞系 | 性别 | 年龄 | 文献 | 外部链接 |
---|---|---|---|---|
EoL-1 | 男 | 33Y | [65] | CVCL_0258 (页面存档备份,存于互联网档案馆) |
HL-60 | 女 | 36Y | [66] | CVCL_0002 (页面存档备份,存于互联网档案馆) |
Kasumi-1 | 男 | 7Y | [67] | CVCL_0589 (页面存档备份,存于互联网档案馆) |
KG-1 | 男 | 59Y | [68] | CVCL_0374 (页面存档备份,存于互联网档案馆) |
NB4 | 女 | 23Y | [69] | CVCL_0005 (页面存档备份,存于互联网档案馆) |
OCI-AML3 | 男 | 57Y | [70] | CVCL_1844 (页面存档备份,存于互联网档案馆) |
SKNO-1 | 男 | 22Y | [71] | CVCL_2196 (页面存档备份,存于互联网档案馆) |
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AML monocytic
More information 细胞系, 性别 ...
细胞系 | 性别 | 年龄 | 文献 | 外部链接 |
---|---|---|---|---|
ME-1 | 男 | 40Y | [72] | CVCL_2110 (页面存档备份,存于互联网档案馆) |
MOLM-13 | 男 | 20Y | [73] | CVCL_2119 (页面存档备份,存于互联网档案馆) |
Mono-Mac-6 | 男 | 64Y | [74] | CVCL_1426 (页面存档备份,存于互联网档案馆) |
MUTZ-3 | 男 | 29Y | [75] | CVCL_1433 (页面存档备份,存于互联网档案馆) |
THP-1 | 男 | 1Y | [76] | CVCL_0006 (页面存档备份,存于互联网档案馆) |
U-937 | 男 | 37Y | [77] | CVCL_0007 (页面存档备份,存于互联网档案馆) |
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AML erythroid
More information 细胞系, 性别 ...
细胞系 | 性别 | 年龄 | 文献 | 外部链接 |
---|---|---|---|---|
F-36P | 男 | 68Y | [78] | CVCL_2037 (页面存档备份,存于互联网档案馆) |
HEL | 男 | 30Y | [79] | CVCL_0001 (页面存档备份,存于互联网档案馆) |
OCI-M2 | 未知 | 56Y | [80] | CVCL_2150 (页面存档备份,存于互联网档案馆) |
TF-1 | 男 | 35Y | [81] | CVCL_0559 (页面存档备份,存于互联网档案馆) |
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AML megakaryocytic
More information 细胞系, 性别 ...
细胞系 | 性别 | 年龄 | 文献 | 外部链接 |
---|---|---|---|---|
CMK | 男 | 10M | [82][83] | CVCL_0216 (页面存档备份,存于互联网档案馆) |
ELF-153 | 男 | 41Y | [84] | CVCL_2031 (页面存档备份,存于互联网档案馆) |
M-07e | 女 | 6M | [85] | CVCL_2106 (页面存档备份,存于互联网档案馆) |
MEGAL | 女 | 未知 | [86] | CVCL_1833 (页面存档备份,存于互联网档案馆) |
MKPL-1 | 男 | 66Y | [87] | CVCL_2116 (页面存档备份,存于互联网档案馆) |
UT-7 | 男 | 64Y | [83] | CVCL_2233 (页面存档备份,存于互联网档案馆) |
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CML myeloid BC
More information 细胞系, 性别 ...
细胞系 | 性别 | 年龄 | 文献 | 外部链接 |
---|---|---|---|---|
EM-2 | 女 | 5Y | [88] | CVCL_1196 (页面存档备份,存于互联网档案馆) |
K-562 | 女 | 53Y | [89][90] | CVCL_0004 (页面存档备份,存于互联网档案馆) |
KCL-22 | 女 | 32Y | [91] | CVCL_2091 (页面存档备份,存于互联网档案馆) |
Ku812 | 男 | 38Y | [92] | CVCL_0379 (页面存档备份,存于互联网档案馆) |
LAMA-84 | 女 | 29Y | [93] | CVCL_0388 (页面存档备份,存于互联网档案馆) |
MOLM-20 | 女 | 63Y | [86] | CVCL_2121 (页面存档备份,存于互联网档案馆) |
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CML lymphoid BC
More information 细胞系, 性别 ...
细胞系 | 性别 | 年龄 | 文献 | 外部链接 |
---|---|---|---|---|
BV-173 | 男 | 45Y | [94] | CVCL_0181 (页面存档备份,存于互联网档案馆) |
CML-T1 | 女 | 36Y | [95] | CVCL_1126 (页面存档备份,存于互联网档案馆) |
NALM-1 | 女 | 3Y | [96] | CVCL_0091[失效链接] |
TK-6 | 男 | 30Y | [97] | CVCL_X907 (页面存档备份,存于互联网档案馆) |
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另见
- NCI-60,国家癌症研究所(NCI)列出的60种人类癌细胞系列表
- ICBP43,NCI的“癌症生物学综合计划”(Integrative Cancer Biology Program)列出的43种人类乳腺癌细胞系列表
参考文献
- Quentmeier, H; Pommerenke, C; Dirks, WG; Eberth, S; Koeppel, M; MacLeod, RAF; Nagel, S; Steube, K; Uphoff, CC; Drexler, HG. The LL-100 panel: 100 cell lines for blood cancer studies.. Scientific Reports. 3 June 2019, 9 (1): 8218. Bibcode:2019NatSR...9.8218Q. PMC 6547646 . PMID 31160637. doi:10.1038/s41598-019-44491-x.
- Drexler, HG; Quentmeier, H. The LL-100 Cell Lines Panel: Tool for Molecular Leukemia-Lymphoma Research.. International Journal of Molecular Sciences. 13 August 2020, 21 (16): 5800. PMC 7461097 . PMID 32823535. doi:10.3390/ijms21165800 .
- Findley HW, Jr; Cooper, MD; Kim, TH; Alvarado, C; Ragab, AH. Two new acute lymphoblastic leukemia cell lines with early B-cell phenotypes.. Blood. December 1982, 60 (6): 1305–9. PMID 6982733. doi:10.1182/blood.V60.6.1305.1305 .
- Uphoff, CC; MacLeod, RA; Denkmann, SA; Golub, TR; Borkhardt, A; Janssen, JW; Drexler, HG. Occurrence of TEL-AML1 fusion resulting from (12;21) translocation in human early B-lineage leukemia cell lines.. Leukemia. March 1997, 11 (3): 441–7. PMID 9067587. S2CID 37823510. doi:10.1038/sj.leu.2400571.
- Hurwitz, R; Hozier, J; LeBien, T; Minowada, J; Gajl-Peczalska, K; Kubonishi, I; Kersey, J. Characterization of a leukemic cell line of the pre-B phenotype.. International Journal of Cancer. February 1979, 23 (2): 174–80. PMID 83966. S2CID 29853203. doi:10.1002/ijc.2910230206.
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- Greil, J; Gramatzki, M; Burger, R; Marschalek, R; Peltner, M; Trautmann, U; Hansen-Hagge, TE; Bartram, CR; Fey, GH; Stehr, K. The acute lymphoblastic leukaemia cell line SEM with t(4;11) chromosomal rearrangement is biphenotypic and responsive to interleukin-7.. British Journal of Haematology. February 1994, 86 (2): 275–83. PMID 8199015. S2CID 44321104. doi:10.1111/j.1365-2141.1994.tb04726.x.
- Menezes, J; Leibold, W; Klein, G; Clements, G. Establishment and characterization of an Epstein-Barr virus (EBC)-negative lymphoblastoid B cell line (BJA-B) from an exceptional, EBV-genome-negative African Burkitt's lymphoma.. Biomédicine. July 1975, 22 (4): 276–84. PMID 179629.
- Nadkarni, JS; Nadkarni, JJ; Clifford, P; Manolov, G; Fenyö, EM; Klein, E. Characteristics of new cell lines derived from Burkitt lymphomas.. Cancer. January 1969, 23 (1): 64–79. PMID 4178827. S2CID 46405882. doi:10.1002/1097-0142(196901)23:1<64::aid-cncr2820230107>3.0.co;2-m .
- PULVERTAFT, JV. Cytology of Burkitt's Tumour (African Lymphoma). Lancet. 1 February 1964, 1 (7327): 238–40. PMID 14086209. doi:10.1016/s0140-6736(64)92345-1.
- Klein, G; Giovanella, B; Westman, A; Stehlin, JS; Mumford, D. An EBV-genome-negative cell line established from an American Burkitt lymphoma; receptor characteristics. EBV infectibility and permanent conversion into EBV-positive sublines by in vitro infection.. Intervirology. 1975, 5 (6): 319–34. PMID 181343. doi:10.1159/000149930.
- Kerckaert, JP; Deweindt, C; Tilly, H; Quief, S; Lecocq, G; Bastard, C. LAZ3, a novel zinc-finger encoding gene, is disrupted by recurring chromosome 3q27 translocations in human lymphomas.. Nature Genetics. September 1993, 5 (1): 66–70. PMID 8220427. S2CID 12575122. doi:10.1038/ng0993-66.
- Rosén, A; Bergh, AC; Gogok, P; Evaldsson, C; Myhrinder, AL; Hellqvist, E; Rasul, A; Björkholm, M; Jansson, M; Mansouri, L; Liu, A; Teh, BT; Rosenquist, R; Klein, E. Lymphoblastoid cell line with B1 cell characteristics established from a chronic lymphocytic leukemia clone by in vitro EBV infection.. Oncoimmunology. 1 January 2012, 1 (1): 18–27. PMC 3376971 . PMID 22720208. doi:10.4161/onci.1.1.18400.
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