Gonadoliberin

Gonadotropin-rilizing-gormon (boshqa nomlari: gonadorelin, gonadoliberin, gonadotropin-rilizing-faktor; qisqartmasi GnRG) gipotalamus rilizing-gormonlari sinfi vakillaridan biridir.

GNRH1
Identifikatorlar
Nomenklatura	GNRH1, GNRH, GRH, HH12, LHRH, LNRH, gonadotropin releasing hormone 1, Gonadotropin-Releasing Hormone
Tashqi IDlar	OMIM: 152760 MGI: 95789 HomoloGene: 641 GeneCards: GNRH1
Gen joylashuvi (odam) Xr. Chromosome 8 (human)[1] Lokus 8p21.2 Bosh. 25,419,258 bp[1] Oxir. 25,424,654 bp[1]
Gen joylashuvi (sichqon) Xr. Chromosome 14 (mouse)[2] Lokus 14|14 D1 Bosh. 67,982,630 bp[2] Oxir. 67,986,888 bp[2]
RNK ekspressiyasi profili Bgee Odam Sichqon (ortolog) Top expressed in tibial nerve Moyak cerebellar hemisphere putamen ascending aorta Descending thoracic aorta mucosa of transverse colon right hemisphere of cerebellum popliteal artery tibial arteries Top expressed in primary oocyte Koʻmik embryonic cell Zigota secondary oocyte morula neural layer of retina Granulotsitlar thymus preoptic area More reference expression data BioGPS More reference expression data
Gen ontologiyasi Molecular function hormone activity gonadotropin hormone-releasing hormone activity gonadotropin-releasing hormone receptor binding Cellular component axon terminus perikaryon Golgi-associated vesicle extracellular region neurosecretory vesicle Dendrit Mitoxondriya neuron projection cytoplasmic side of rough endoplasmic reticulum membrane extracellular space Biological process negative regulation of immature T cell proliferation response to prolactin negative regulation of neuron migration response to potassium ion response to organic cyclic compound response to testosterone estrous cycle female pregnancy cell-cell signaling response to steroid hormone ageing response to peptide hormone negative regulation of apoptotic process male sex determination multicellular organism development response to prostaglandin E response to lipopolysaccharide response to corticosteroid regulation of gene expression ovulation cycle response to ethanol regulation of ovarian follicle development signal transduction negative regulation of cell population proliferation regulation of signaling receptor activity G protein-coupled receptor signaling pathway Koʻpayish Sources:Amigo / QuickGO
Ortologiya Turlar Odam Sichqon Entrez 2796 14714 Ensembl ENSG00000147437 ENSMUSG00000015812 UniProt P01148 P13562 RefSeq (mRNK) NM_001083111 NM_000825 NM_008145 RefSeq (protein) NP_000816 NP_001076580 NP_032171 Location (UCSC) Chr 8: 25.42 – 25.42 Mb Chr 14: 67.98 – 67.99 Mb PubMed [3] [4]
Vikimaʼlumotlar
koʻrish/tahrirlash (odam) koʻrish/tahrirlash (sichqon)