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Ang kromosomang 3 o kulaylawas[1] na 3 (Ingles: Chromosome 3) ang isa sa 23 mga pares ng kromosoma sa mga tao. Ang mga tao ay normal na mayroong dalawang kopya ng kromosomang ito. Ang kromosomang 3 ay sumasaklaw sa halos 200 milyong mga base na pares na pantayong materyal ng DNA at kumakatawan sa mga 6.5 porsiyento ng kabuuang DNA sa mga selula.
Ang pagtukoy ng mga gene sa bawat kromosoma ay isang aktibong henetikong pagsasaliksik. Dahil sa ang mga mananaliksik ay gumagamit ng iba't ibang mga paraan sa paghula ng bilang ng mga gene sa bawat kromosoma, ang tinantiyang bilang ng mga gene ay iba iba. Ang kromosomang 3 ay malamang na naglalaman sa pagitan ng 1,100 at 1,500 mga gene.
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Ang mga sumusunod ang ilan sa mga gene na matatagpuan sa kromosomang 3:
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- ALAS1: aminolevulinate, delta-, synthase 1
- BTD: biotinidase
- CCR5: chemokine (C-C motif) receptor 5
- CNTN4: Contactin 4
- COL7A1: Collagen, type VII, alpha 1 (epidermolysis bullosa, dystrophic, dominant and recessive)
- C3orf14-Chromosome 3 open reading frame 14: predicted DNA binding protein.
- MITF: microphthalmia-associated transcription factor
- MLH1: mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli)
- OXTR: oxytocin receptor
- PTHR1: parathyroid hormone receptor 1
- SCN5A: sodium channel, voltage-gated, type V, alpha (long QT syndrome 3)
- SLC25A20: solute carrier family 25 (carnitine/acylcarnitine translocase), member 20
- TMIE: transmembrane inner ear
- VHL: von Hippel-Lindau tumor suppressor
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- ADIPOQ: adiponectin
- CPOX: coproporphyrinogen oxidase (coproporphyria, harderoporphyria)
- HGD: homogentisate 1,2-dioxygenase (homogentisate oxidase)
- IFT122: intraflagellar transport gene 122
- MCCC1: methylcrotonoyl-Coenzyme A carboxylase 1 (alpha)
- PCCB: propionyl Coenzyme A carboxylase, beta polypeptide
- PDCD10: programmed cell death 10
- PIK3CA: phosphoinositide-3-kinase, catalytic, alpha polypeptide
- RAB7: RAB7, member RAS oncogene family
- RHO: rhodopsin visual pigment
- SOX2: transcription factor
- USH3A: Usher syndrome 3A
- ZNF9: zinc finger protein 9 (a cellular retroviral nucleic acid binding protein)
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Ang mga sumusunod na sakit ang ilan sa mga nauugnay sa mga gene sa kromosomang 3:
- 3-methylcrotonyl-CoA carboxylase deficiency
- 3q29 microdeletion syndrome
- Alkaptonuria
- Arrhythmogenic right ventricular dysplasia
- Atransferrinemia
- Autism
- Biotinidase deficiency
- Blepharophimosis, epicanthus inversus and ptosis type 1
- Breast/colon/lung/pancreatic cancer
- Brugada syndrome
- Castillo fever
- Carnitine-acylcarnitine translocase deficiency
- Cataracts
- Cerebral cavernous malformation
- Charcot-Marie-Tooth disease, type 2
- Charcot-Marie-Tooth disease
- Chromosome 3q duplication syndrome
- Coproporphyria
- Deafness
- Diabetes
- Dopamine receptor
- Dystrophic epidermolysis bullosa
- Endplate acetlycholinesterase deficiency
- Essential tremors
- Glaucoma, primary open angle
- Glycogen storage disease
- Hailey-Hailey disease
- Harderoporphyrinuria
- Heart block, progressive/nonprogressive
- Hereditary coproporphyria
- Hereditary nonpolyposis colorectal cancer
- HIV infection, susceptibility/resistance to
- Hypobetalipoproteinemia, familial
- Hypothermia
- Leukoencephalopathy with vanishing white matter
- Long QT syndrome
- Lymphomas
- Malignant hyperthermia susceptibility
- Metaphyseal chondrodysplasia, Murk Jansen type
- Moebius syndrome
- Moyamoya disease
- Mucopolysaccharidosis
- Muir-Torre family cancer syndrome
- Myotonic dystrophy, type 2
- Myotonic dystrophy
- Neuropathy, hereditary motor and sensory, Okinawa type
- Night blindness
- Nonsyndromic deafness, autosomal recessive
- Nonsyndromic deafness
- Ovarian cancer
- Porphyria
- Propionic acidemia
- Protein S deficiency
- Pseudo-Zellweger syndrome
- Retinitis pigmentosa
- Romano-Ward syndrome
- Sensenbrenner syndrome
- Septo-optic dysplasia
- Short stature
- Spinocerebellar ataxia
- Sucrose intolerance
- T-cell leukemia translocation altered gene
- Usher syndrome type III
- Usher syndrome (Finland)
- Usher syndrome
- von Hippel-Lindau syndrome
- Waardenburg syndrome
- Xeroderma pigmentosum, complementation group c
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