Sterol O-aciltransferaza

Sterol O-aciltransferaza (EC 2.3.1.26, holestarolna aciltransferaza, sterol-estarska sintaza, sterol-estarska sintetaza, sterol-estarska sintaza, acil koenzim A-holestarol-O-aciltransferaza, acil-KoA:holestarol aciltransferaza, , acilkoenzim A:holestarol O-aciltransferaza, holestarol estarska sintaza, holestarol estarska sintetaza, holestaril estarska sintetaza) je enzim sa sistematskim imenom acil-KoA:holestarol O-aciltransferaza.^[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju

acil-KoA + holesterol ${\displaystyle \rightleftharpoons }$ KoA + holesterol estar

Sterol O-aciltransferaza
Identifikatori
EC broj	2.3.1.26
CAS broj	9027-63-8
Baze podataka
IntEnz	IntEnz pregled
BRENDA	BRENDA pristup
ExPASy	NiceZyme pregled
KEGG	KEGG pristup
MetaCyc	metabolički put
PRIAM	profil
Strukture PBP	RCSB PDB PDBe PDBj PDBsum
Pretraga PMC članci PubMed članci NCBI proteini

Životinjski enzim je visoko specifičan za transfer acil grupa.

Reference

1. Sgoutas, D.S. (1970). „Effect of geometry and position of ethylenic bond upon acyl coenzymeA^--cholesterol-O-acyltransferase”. Biochemistry. 9: 1826—1833. PMID 5439042.
2. Spector, A.A., Mathur, S.N. and Kaduce, T.L. (1979). „Role of acylcoenzyme A: cholesterol O-acyltransferase in cholesterol metabolism”. Prog. Lipid Res. 18: 31—53. PMID 42927.CS1 одржавање: Вишеструка имена: списак аутора (веза)
3. Taketani, S., Nishino, T. and Katsuki, H. (1979). „Characterization of sterol-ester synthetase in Saccharomyces cerevisiae”. Biochim. Biophys. Acta. 575: 148—155. PMID 389289.CS1 одржавање: Вишеструка имена: списак аутора (веза)

Literatura

• Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
• Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
• Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
• Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
• William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605.

Spoljašnje veze

• Sterol+O-acyltransferase на ()