Piruvat dehidrogenaza (citohrom)

Piruvat dehidrogenaza (citohrom) (EC 1.2.2.2, piruvatna dehidrogenaza, piruvinska dehidrogenaza, piruvinska (citohrom b1) dehidrogenaza, piruvat:ubihinon-8-oksidoreduktaza, piruvatna oksidaza (nespecifična)) je enzim sa sistematskim imenom piruvat:fericitohrom-b1 oksidoreduktaza.^[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju:

piruvat + fericitohrom b1 +₂O ${\displaystyle \rightleftharpoons }$ acetat + ₂ + ferocitohrom b1

Piruvat dehidrogenaza (citohrom)
Identifikatori
EC broj	1.2.2.2
CAS broj	9079-84-9
Baze podataka
IntEnz	IntEnz pregled
BRENDA	BRENDA pristup
ExPASy	NiceZyme pregled
KEGG	KEGG pristup
MetaCyc	metabolički put
PRIAM	profil
Strukture PBP	RCSB PDB PDBe PDBj PDBsum
Pretraga PMC članci PubMed članci NCBI proteini

Ovaj enzim je flavoprotein. Za njegovo dejstvo je neophodan tiamin difosfat.

Reference

1. Williams, F.R. & Hager, L.P. (1961). „A crystalline flavin pyruvate oxidase”. J. Biol. Chem. 236: PC36—PC37. PMID 13785427.
2. Koland, J.G. & Gennis, R.B. (1982). „Identification of an active site cysteine residue in Escherichia coli pyruvate oxidase”. J. Biol. Chem. 257: 6023—6027. PMID 7042705.

Literatura

• Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
• Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
• Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
• Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
• William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605.

Spoljašnje veze

• Pyruvate+dehydrogenase+(cytochrome) на ()