5-1 receptori su potfamilija 5- receptora koji vezuju endogeni neurotransmiter serotonin (5-hidrokstriptamin, 5-).[1] 5-1 potfamilija sadrži pet G protein-spregnutih receptora koji vezuju i posreduju inhibitornu neurotransmisiju.[2] Ova grupa obuhvata 5-1A, 5-1B, 5-1D, 5-1E, i . Ne postoji receptor, jer je njegova klasifikacija promenjena u receptor.
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