Pyrimidine

Pyrimidines include three of the bases in DNA and RNA.

Pyrimidine

Names
IUPAC name Pyrimidine
Other names 1,3-Diazine, m-Diazine
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references

A pyrimidine is an aromatic heterocyclic organic compound, similar to purine.^[1] It has nitrogens at positions 1 and 3 in the ring.^[2][3]

Pyrimidines

The pyrimidine ring system occurs widely in nature.^[4]

• Cytosine (C),
• Thymine (T),
• Uracil (U).
• Thiamine (vitamin B1)

It is also found in many synthetic compounds such as barbiturates and the HIV drug, zidovudine. Uric acid is a pyrimidine derivative.

References

1. Gilchrist T.L. (1997). Heterocyclic chemistry. New York: Longman. ISBN 0-582-27843-0.
2. Joule, John A.; Mills, Keith, eds. (2010). Heterocyclic chemistry (5th ed.). Oxford: Wiley. p. 250. ISBN 978-1-405-13300-5.
3. Brown H.C. et al 1955. In Baude, E.A. and Nachod, F.C., Determination of organic structures by physical methods. Academic Press, New York.
4. Lagoja, Irene M. (2007). "Pyrimidine as constituent of natural biologically active compounds" (PDF). Chemistry and Biodiversity. 2 (1): 1–50. doi:10.1002/cbdv.200490173. PMID 17191918. S2CID 9942715. Archived from the original (PDF) on 2017-02-15. Retrieved 2014-10-05.