Dipeptide

A dipeptide is a kind of organic compound (and therefore a kind of molecule).^[1] A dipeptide is made up of only two amino acids: one amino acid on each side of a peptide bond. A dipeptide can be made from two different amino acids or by two amino acids of the same kind. A peptide bond will be in between the two amino acids.

Skeletal formula of Gly-Gly. The peptide bond is between the carbon that is double bonded to the oxygen, and the nitrogen.

Gly-Gly, or Glycylglycine is a dipeptide and also the simplest peptide. It is the dipeptide of Glycine.^[2]

List of dipeptides

Some of the dipeptides are

• aspartame, an artificial sweetener.^[3]

• Acetylcarnosine, cataract prevention^[3]
• Advantame
• Ala-Gln, infusion^[4]
• Alafosfalin
• Alanyl-glutamine
• Aloxistatin
• Andrimid
• Anserine are highly concentrated in muscle and brain tissues. They are used in sports medicines.^[3]
  • • Homoanserine, found in the brain and muscles of mammals
• Argininosuccinic acid
• BNC-210
• Carnosine are highly concentrated in muscle and brain tissues. They are used in sports medicines.^[3]
• DAPT (chemical)
• Diphenylalanine is a well-known building block in peptide nanotechnology
• E-64
• Gly-Tyr, infusion^[4]
• Glycylglycine
• Hypoglycin B
• imidazole-dipeptide^[5] (related page Imidazole)
• Kyotorphin is a neuroactive dipeptide which plays a role in pain regulation in the brain.
• Melphalan flufenamide
• Neotame
• Val-Tyr, antihypertensive^[3]
• Balenine [ja] (or ophidine) has been identified in the muscles of several species of mammal (including man), and the chicken.
• Glorin is a chemotactic dipeptide for the slime mold Polysphondylium violaceum.
• Barettin is a cyclic dipeptide from the marine sponge Geodia barretti.
• Pseudoproline
• Dialanine is commonly used as a model in molecular dynamics.
• Xenortides, isolated from the bacterium Xenorhabdus nematophila

Related page

• Peptide bond

References

1. https://www.bionity.com/en/encyclopedia/Dipeptide.html#:~:text=A%20dipeptide%20is%20a%20molecule,by%20a%20single%20peptide%20bond. Bionity.com. Retrieved 2023-02-25
2. https://onlinelibrary.wiley.com/doi/abs/10.1002/anie.201702425. Wiley Online Library. Retrieved 2023-02-26
3. Yagasaki M, Hashimoto S (November 2008). "Synthesis and application of dipeptides; current status and perspectives". Applied Microbiology and Biotechnology. 81 (1): 13–22. doi:10.1007/s00253-008-1590-3. PMID 18795289.
4. Fürst P, Pogan K, Stehle P (1997). "Glutamine dipeptides in clinical nutrition". Nutrition. 13 (7–8): 731–7. doi:10.1016/S0899-9007(97)83035-3. PMID 9263278.
5. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7912684/. National Institutes of Health. Retrieved 2023-02-25