O rotavirus de proteína não estrutural viral NSP4 foi a primeira enterotoxina descoberta. Esta provoca diarreia e causa secreção transepitelial dependente de Ca2+.[1]
Referências
- Dong, Y.; Zeng, CQ; Ball, JM; Estes, MK; Morris, AP (1997). «The rotavirus enterotoxin NSP4 mobilizes intracellular calcium in human intestinal cells by stimulating phospholipase C-mediated inositol 1,4,5-trisphosphate production». Proceedings of the National Academy of Sciences. 94 (8): 3960–5. PMC 20550
. PMID 9108087. doi:10.1073/pnas.94.8.3960
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