CACNA2D1

CACNA2D1
Identificadores
Nomes alternativos	CACNA2D1
IDs externos	OMIM: 114204 HomoloGene: 579 GeneCards: CACNA2D1
Doenças Geneticamente Relacionadas
	obesidade, colite ulcerosa, fígado gorduroso
Targeted by Drug
	bepridil hydrochloride monohydrate
Ontologia genética
Função molecular	• voltage-gated calcium channel activity; • metal ion binding; • voltage-gated ion channel activity; • calcium channel activity; • voltage-gated calcium channel activity involved in cardiac muscle cell action potential; • voltage-gated calcium channel activity involved in bundle of His cell action potential;
Componente celular	• Canal de cálcio dependente de voltagem; • L-type voltage-gated calcium channel complex; • integral component of membrane; • túbulo-T; • membrana plasmática; • Exossoma; • membrane; • retículo sarcoplasmático;
Processo biológico	• regulation of ion transmembrane transport; • regulation of calcium ion transport; • cardiac conduction; • ion transport; • calcium ion transmembrane transport; • calcium ion transport; • GO:0015915 transport; • cardiac muscle cell action potential involved in contraction; • calcium ion transport into cytosol; • positive regulation of high voltage-gated calcium channel activity; • regulation of heart rate by cardiac conduction; • calcium ion transmembrane transport via high voltage-gated calcium channel; • regulation of ventricular cardiac muscle cell membrane repolarization; • regulation of membrane repolarization during action potential; • membrane depolarization during bundle of His cell action potential; • calcium ion import across plasma membrane; • regulation of calcium ion transmembrane transport via high voltage-gated calcium channel; • cellular response to amyloid-beta;
	Sources:Amigo / QuickGO
Padrão de expressão RNA
	Mais dados de referência de expressão
Ortólogos
	781
	n/a
	ENSG00000153956
	n/a
	P54289
	n/a
	NM_000722; NM_001302890; NM_001366867
	n/a
	NP_000713; NP_001289819; NP_001353796
	n/a
	Wikidata
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