compositum chemicum From Wikipedia, the free encyclopedia
Clopidogrelum est substantia aggregrans, hinc etiam substantia anticoagulans in vasibus sanguineis operans ad prophylaxem apoplexiae cerebri et infarctus cordis, quo interdum una cum acido acetylosalicylico adhibetur. Effectus usque ad quinque dies continuat.
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Cave: notitiae huius paginae nec praescriptiones nec consilia medica sunt. |
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| Natura chemica | |
|---|---|
| Formula chemica | C 16H 16ClNO 2S |
| Massa molaris | 321.82 g/mol |
| PubChem | 60606 |
| DrugBank | DB00758 |
| Natura pharmacologica | |
| Codex ATC | B01AC04 (WHO) |
| Tempus semivitae biologicum | 7-8 h |
| Continuatio efficiendi | 5 d |
| Metabolismus | iecore (hepaticus) |
| Excretio | faecibus: 46%, renibus: 50% |
| Ad usum therapeuticum | |
| Applicatio | per os |
| MedlinePlus | a601040 (Anglice) |
In metabolismo Clopidogrelum est substantia praecursor, primum per CYP2C19, CYP1A2, CYP2B6, alterum per CYP2C19, CYP2C9, CYP2B6, CYP3A4 activatum.
Clopidogrelum in ordinis mundi sanitarii indicem exemplarem medicamentorum essentialium receptum est.
Clopidogrelum est (S)-methylo-(2-chlorphenylo)-2-(6,7-dihydro-4H-thieno-[3,2-c]-pyridino-5-yl)-acetatum (nomen IUPAC).
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