LKB1

STK11
PDBに登録されている構造
PDB	オルソログ検索: RCSB PDBe PDBj
PDBのIDコード一覧
	2WTK, 4ZDR
識別子
記号	STK11, LKB1, PJS, hLKB1, serine/threonine kinase 11
外部ID	OMIM: 602216 MGI: 1341870 HomoloGene: 393 GeneCards: STK11
遺伝子の位置 (ヒト)
染色体	19番染色体 (ヒト)
終点	1,228,431 bp
遺伝子の位置 (マウス)
染色体	10番染色体 (マウス)
終点	79,966,516 bp
RNA発現パターン
	; ;
	さらなる参照発現データ
遺伝子オントロジー
分子機能	• トランスフェラーゼ活性; • ヌクレオチド結合; • LRR domain binding; • protein kinase activity; • p53結合; • protein kinase activator activity; • 金属イオン結合; • キナーゼ活性; • protein serine/threonine kinase activity; • 血漿タンパク結合; • ATP binding; • magnesium ion binding;
細胞の構成要素	• 細胞質; • 膜; • ミトコンドリア; • エキソソーム; • TCR signalosome; • 細胞核; • 核質; • 細胞質基質;
生物学的プロセス	• response to ionizing radiation; • positive regulation of transforming growth factor beta receptor signaling pathway; • dendrite extension; • TCR signalosome assembly; • axonogenesis; • glucose homeostasis; • positive regulation of autophagy; • リン酸化; • negative regulation of lipid biosynthetic process; • positive regulation of axonogenesis; • cellular response to DNA damage stimulus; • regulation of dendrite morphogenesis; • オートファジー; • タンパク質リン酸化; • Golgi localization; • regulation of Wnt signaling pathway; • 脈管構造発生; • アノイキス; • cellular response to UV-B; • negative regulation of cell growth; • regulation of cell growth; • tissue homeostasis; • establishment of cell polarity; • positive thymic T cell selection; • positive regulation of peptidyl-tyrosine phosphorylation; • regulation of protein kinase B signaling; • canonical Wnt signaling pathway; • intrinsic apoptotic signaling pathway by p53 class mediator; • 自己リン酸化; • 細胞周期; • negative regulation of epithelial cell proliferation involved in prostate gland development; • T cell receptor signaling pathway; • 精子形成; • activation of protein kinase activity; • negative regulation of TORC1 signaling; • negative regulation of cell population proliferation; • positive regulation of protein localization to nucleus; • アポトーシス; • regulation of signal transduction by p53 class mediator; • 神経系発生; • peptidyl-serine phosphorylation; • peptidyl-threonine phosphorylation; • 細胞分化; • positive regulation of protein serine/threonine kinase activity; • protein dephosphorylation; • negative regulation of canonical Wnt signaling pathway; • negative regulation of cold-induced thermogenesis;
	出典:Amigo / QuickGO
オルソログ
	6794
	20869
	ENSG00000118046
	ENSMUSG00000003068
	Q15831
	Q9WTK7
	NM_000455
	NM_001301853; NM_001301854; NM_011492
	NP_000446
	NP_001288782; NP_001288783; NP_035622
	ウィキデータ
閲覧/編集ヒト	閲覧/編集マウス