Nella tabella sottostante sono riportati i risultati delle finali del singolare femminile del torneo US Open di tennis.
| Anno | Vincitrice | Finalista | Punteggio |
| 1887 |  Ellen Hansell | Laura Knight | 6–1, 6–0 |
| 1888 | Bertha Townsend (1) | Ellen Hansell | 6–3, 6–5 |
| 1889 | Bertha Townsend (2) | Lida Voorhees | 7–5, 6–2 |
| 1890 | Ellen Roosevelt | Bertha Townsend | 6–2, 6–2 |
| 1891 |  Mabel Cahill (1) | Ellen Roosevelt | 6–4, 6–1, 4–6, 6–3 |
| 1892 | Mabel Cahill (2) | Elisabeth Moore | 5–7, 6–3, 6–4, 4–6, 6–2 |
| 1893 | Aline Terry | Augusta Schultz | 6–1, 6–3 |
| 1894 | Helen Hellwig | Aline Terry | 7–5, 3–6, 6–0, 3–6, 6–3 |
| 1895 | Juliette Atkinson (1) | Helen Hellwig | 6–4, 6–2, 6–1 |
| 1896 | Elisabeth Moore (1) | Juliette Atkinson | 6–4, 4–6, 6–2, 6–2 |
| 1897 | Juliette Atkinson (2) | Elisabeth Moore | 6–3, 6–3, 4–6, 3–6, 6–3 |
| 1898 | Juliette Atkinson (3) | Marion Jones | 6–3, 5–7, 6–4, 2–6, 7–5 |
| 1899 | Marion Jones (1) | Maud Banks | 6–1, 6–1, 7–5 |
| 1900 | Myrtle McAteer | Edith Parker | 6–2, 6–2, 6–0 |
| 1901 | Elisabeth Moore (2) | Myrtle McAteer | 6–4, 3–6, 7–5, 2–6, 6–2 |
| 1902 | Marion Jones (2) | Elisabeth Moore | 6–1, 1–0 ritiro |
| 1903 | Elisabeth Moore (3) | Marion Jones | 7–5, 8–6 |
| 1904 | May Sutton | Elisabeth Moore | 6–1, 6–2 |
| 1905 | Elisabeth Moore (4) | Helen Homans | 6–4, 5–7, 6–1 |
| 1906 | Helen Homans | Maud Barger-Wallach | 6–4, 6–3 |
| 1907 | Evelyn Sears | Carrie Neely | 6–3, 6–2 |
| 1908 | Maud Barger-Wallach | Evelyn Sears | 6–3, 1–6, 6–3 |
| 1909 | Hazel Hotchkiss Wightman (1) | Maud Barger-Wallach | 6–0, 6–1 |
| 1910 | Hazel Hotchkiss Wightman (2) | Louise Hammond | 6–4, 6–2 |
| 1911 | Hazel Hotchkiss Wightman (3) | Florence Sutton | 8–10, 6–1, 9–7 |
| 1912 |  Mary Browne (1) | Eleonora Sears | 6–4, 6–2 |
| 1913 | Mary Browne (2) | Dorothy Green | 6–2, 7–5 |
| 1914 | Mary Browne (3) | Marie Wagner | 6–2, 1–6, 6–1 |
| 1915 |  Molla Bjurstedt (1) | Hazel Hotchkiss Wightman | 4–6, 6–2, 6–0 |
| 1916 | Molla Bjurstedt (2) | Louise Hammond Raymond | 6–0, 6–1 |
| 1917 | Molla Bjurstedt (3) | Marion Vanderhoef | 4–6, 6–0, 6–2 |
| 1918 | Molla Bjurstedt (4) | Eleanor E. Goss | 6–4, 6–3 |
| 1919 | Hazel Hotchkiss Wightman | Marion Zinderstein | 6–1, 6–2 |
| 1920 | Molla Bjurstedt Mallory (5) | Marion Zinderstein | 6–3, 6–1 |
| 1921 | Molla Bjurstedt Mallory (6) | Mary Browne | 4–6, 6–4, 6–2 |
| 1922 | Molla Bjurstedt Mallory (7) | Helen Wills | 6–3, 6–1 |
| 1923 | Helen Wills (1) | Molla Bjurstedt Mallory | 6–2, 6–1 |
| 1924 | Helen Wills (2) | Molla Bjurstedt Mallory | 6–1, 6–3 |
| 1925 | Helen Wills (3) | Kathleen McKane | 3–6, 6–0, 6–2 |
| 1926 | Molla Bjurstedt Mallory (8) | Elizabeth Ryan | 4–6, 6–4, 9–7 |
| 1927 | Helen Wills (4) | Betty Nuthall | 6–1, 6–4 |
| 1928 | Helen Wills (5) | Helen Jacobs | 6–2, 6–1 |
| 1929 | Helen Wills (6) | Phoebe Holcroft Watson | 6–4, 6–2 |
| 1930 | Betty Nuthall | Anna McCune Harper | 6–1, 6–4 |
| 1931 | Helen Wills Moody (7) | Eileen Bennett Whittingstall | 6–4, 6–1 |
| 1932 | Helen Hull Jacobs (1) | Carolin Babcock | 6–2, 6–2 |
| 1933 | Helen Hull Jacobs (2) | Helen Wills Moody | 8–6, 3–6, 3–0 ritiro |
| 1934 | Helen Hull Jacobs (3) | Sarah Palfrey | 6–1, 6–4 |
| 1935 | Helen Hull Jacobs (4) | Sarah Palfrey Fabyan | 6–2, 6–4 |
| 1936 | Alice Marble (1) | Helen Hull Jacobs | 4–6, 6–3, 6–2 |
| 1937 |  Anita Lizana |  Jadwiga Jędrzejowska | 6–4, 6–2 |
| 1938 | Alice Marble (2) |  Nancye Wynne Bolton | 6–0, 6–3 |
| 1939 | Alice Marble (3) | Helen Hull Jacobs | 6–0, 8–10, 6–4 |
| 1940 | Alice Marble (4) | Helen Hull Jacobs | 6–2, 6–3 |
| 1941 | Sarah Palfrey Cooke (1) | Pauline Betz | 7–5, 6–2 |
| 1942 | Pauline Betz (1) | Louise Brough | 4–6, 6–1, 6–4 |
| 1943 | Pauline Betz (2) | Louise Brough | 6–3, 5–7, 6–3 |
| 1944 | Pauline Betz (3) | Margaret Osborne | 6–3, 8–6 |
| 1945 | Sarah Palfrey Cooke (2) | Pauline Betz | 3–6, 8–6, 6–4 |
| 1946 | Pauline Betz (4) | Patricia Canning | 11–9, 6–3 |
| 1947 | Louise Brough | Margaret Osborne | 8–6, 4–6, 6–1 |
| 1948 | Margaret Osborne duPont (1) | Louise Brough | 4–6, 6–4, 15–13 |
| 1949 | Margaret Osborne duPont (2) | Doris Hart | 6–3, 6–1 |
| 1950 | Margaret Osborne duPont (3) | Doris Hart | 6–4, 6–3 |
| 1951 | Maureen Connolly (1) | Shirley Fry | 6–3, 1–6, 6–4 |
| 1952 | Maureen Connolly (2) | Doris Hart | 6–3, 7–5 |
| 1953 | Maureen Connolly (3) | Doris Hart | 6–2, 6–4 |
| 1954 | Doris Hart (1) | Louise Brough | 6–8, 6–1, 8–6 |
| 1955 | Doris Hart (2) | Patricia Ward | 6–4, 6–2 |
| 1956 | Shirley Fry | Althea Gibson | 6–3, 6–4 |
| 1957 | Althea Gibson (1) | Louise Brough | 6–3, 6–2 |
| 1958 | Althea Gibson (2) | Darlene Hard | 3–6, 6–1, 6–2 |
| 1959 |  Maria Bueno (1) | Christine Truman | 6–1, 6–4 |
| 1960 | Darlene Hard (1) |  Maria Bueno | 6–4, 10–12, 6–4 |
| 1961 | Darlene Hard (2) | Ann Haydon-Jones | 6–3, 6–4 |
| 1962 | Margaret Smith (1) | Darlene Hard | 9–7, 6–4 |
| 1963 | Maria Bueno (2) | Margaret Smith | 7–5, 6–4 |
| 1964 | Maria Bueno (3) | Carole Caldwell Graebner | 6–1, 6–0 |
| 1965 | Margaret Smith (2) | Billie Jean Moffitt | 8–6, 7–5 |
| 1966 | Maria Bueno (4) | Nancy Richey | 6–3, 6–1 |
| 1967 | Billie Jean King (1) | Ann Haydon-Jones | 11–9, 6–4 |
| 1968 | Virginia Wade | Billie Jean King | 6–4, 6–2 |
| 1969 | Margaret Smith Court (3) | Nancy Richey | 6–2, 6–2 |
| 1970 | Margaret Smith Court (4) | Rosemary Casals | 6–2, 2–6, 6–1 |
| 1971 | Billie Jean King (2) | Rosemary Casals | 6–4, 7–6(2) |
| 1972 | Billie Jean King (3) | Kerry Melville | 6–3, 7–5 |
| 1973 | Margaret Smith Court (5) | Evonne Goolagong | 7–6(2), 5–7, 6–2 |
| 1974 | Billie Jean King (4) | Evonne Goolagong | 3–6, 6–3, 7–5 |
| 1975 | Chris Evert (1) | Evonne Goolagong | 5–7, 6–4, 6–2 |
| 1976 | Chris Evert (2) | Evonne Goolagong | 6–3, 6–0 |
| 1977 | Chris Evert (3) | Wendy Turnbull | 7–6(3), 6–2 |
| 1978 | Chris Evert (4) | Pam Shriver | 7–5, 6–4 |
| 1979 | Tracy Austin (1) | Chris Evert Lloyd | 6–4, 6–3 |
| 1980 | Chris Evert Lloyd (1) |  Hana Mandlíková | 5–7, 6–1, 6–1 |
| 1981 | Tracy Austin (2) | Martina Navrátilová | 1–6, 7–6(4), 7–6(1) |
| 1982 | Chris Evert Lloyd (2) | Hana Mandlíková | 6–3, 6–1 |
| 1983 | Martina Navrátilová (1) | Chris Evert Lloyd | 6–1, 6–3 |
| 1984 | Martina Navrátilová (2) | Chris Evert Lloyd | 4–6, 6–4, 6–4 |
| 1985 | Hana Mandlíková | Martina Navrátilová | 7–6(3), 1–6, 7–6(2) |
| 1986 | Martina Navrátilová (3) | Helena Suková | 6–3, 6–2 |
| 1987 | Martina Navrátilová (4) |  Steffi Graf | 7–6(4), 6–1 |
| 1988 | Steffi Graf (1) |  Gabriela Sabatini | 6–3, 3–6, 6–1 |
| 1989 | Steffi Graf (2) | Martina Navrátilová | 3–6, 7–5, 6–1 |
| 1990 | Gabriela Sabatini | Steffi Graf | 6–2, 7–6(4) |
| 1991 |  Monica Seles (1) | Martina Navrátilová | 7–6(1), 6–1 |
| 1992 | Monica Seles (2) |  Arantxa Sánchez Vicario | 6–3, 6–3 |
| 1993 | Steffi Graf (3) | Helena Suková | 6–3, 6–3 |
| 1994 | Arantxa Sánchez Vicario | Steffi Graf | 1–6, 7–6(3), 6–4 |
| 1995 | Steffi Graf (4) | Monica Seles | 7–6(6), 0–6, 6–3 |
| 1996 | Steffi Graf (5) | Monica Seles | 7–5, 6–4 |
| 1997 |  Martina Hingis | Venus Williams | 6–0, 6–4 |
| 1998 | Lindsay Davenport | Martina Hingis | 6–3, 7–5 |
| 1999 | Serena Williams (1) | Martina Hingis | 6–3, 7–6(4) |
| 2000 | Venus Williams (1) | Lindsay Davenport | 6–4, 7–5 |
| 2001 | Venus Williams (2) | Serena Williams | 6–2, 6–4 |
| 2002 | Serena Williams (2) | Venus Williams | 6–4, 6–3 |
| 2003 |  Justine Henin | Kim Clijsters | 7–5, 6–1 |
| 2004 |  Svetlana Kuznecova | Elena Dement'eva | 6–3, 7–5 |
| 2005 | Kim Clijsters (1) |  Mary Pierce | 6–3, 6–1 |
| 2006 | Marija Šarapova | Justine Henin | 6–4, 6–4 |
| 2007 | Justine Henin | Svetlana Kuznecova | 6–1, 6–3 |
| 2008 | Serena Williams (3) |  Jelena Janković | 6–4, 7–5 |
| 2009 | Kim Clijsters (2) |  Caroline Wozniacki | 7–5, 6–3 |
| 2010 | Kim Clijsters (3) | Vera Zvonarëva | 6–2, 6–1 |
| 2011 | Samantha Stosur | Serena Williams | 6–2, 6–3 |
| 2012 | Serena Williams (4) |  Viktoryja Azaranka | 6–2, 2–6, 7–5 |
| 2013 | Serena Williams (5) | Viktoryja Azaranka | 7–5, 6(6)–7, 6–1 |
| 2014 | Serena Williams (6) | Caroline Wozniacki | 6–3, 6–3 |
| 2015 |  Flavia Pennetta | Roberta Vinci | 7–6(4), 6–2 |
| 2016 | Angelique Kerber | Karolína Plíšková | 6–3, 4–6, 6–4 |
| 2017 | Sloane Stephens | Madison Keys | 6–3, 6–0 |
| 2018 |  Naomi Ōsaka (1) | Serena Williams | 6–2, 6–4 |
| 2019 |  Bianca Andreescu | Serena Williams | 6–3, 7–5 |
| 2020 | Naomi Ōsaka (2) | Viktoryja Azaranka | 1–6, 6–3, 6–3 |
| 2021 | Emma Raducanu | Leylah Annie Fernandez | 6–4, 6–3 |
| 2022 | Iga Świątek |  Ons Jabeur | 6–2, 7–6(5) |
| 2023 |
Coco Gauff |
 Aryna Sabalenka |
2–6, 6–3, 6–2 |
| 2024 |
Aryna Sabalenka |
Jessica Pegula |
7–5, 7–5 |
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