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Statins, wanda kuma aka sani da HMG-CoA reductase inhibitors, wani nau'in magani ne da aka fi amfani da shi don hauhawar cholesterol da cututtukan zuciya.[1] Ana amfani da su duka don hana cututtukan zuciya a cikin waɗanda ke cikin haɗari mai yawa, da kuma waɗanda ke da cututtukan zuciya.[2][3] Ana ɗauke su da baki.[1]
Statin | |
---|---|
drug class (en) da group or class of chemical entities (en) | |
Bayanai | |
Ƙaramin ɓangare na | magani, anticholesteremic agents (en) , enzyme inhibitor (en) da oxidoreductase inhibitor (en) |
Bangare na | response to statin (en) |
Abubuwan da ake amfani da su sun haɗa da ciwon kai, maƙarƙashiya, da tashin hankali.[4] Mummunan illa na iya haɗawa da raunin tsoka, matsalolin hanta, da ciwon sukari mellitus.[4][5] Ba a ba da shawarar yin amfani da lokacin daukar ciki ko shayarwa ba.[1] Suna hana HMG-CoA reductase enzyme wanda ke rage samar da cholesterol da triglycerides.[1]
An gano Statins a cikin 1971 kuma lovastatin ya shiga aikin likita a cikin 1987.[2][6] Akwai adadin statins a matsayin magani na gama-gari kuma ba su da tsada.[1] Su ne mafi yawan magungunan rage ƙwayar cholesterol.[7] A cikin 2018 atorvastatin shine mafi yawan magunguna a Amurka kuma simvastatin shine na 10 mafi yawan wajabta.[8]
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