Prednisolone

Prednisolone magani ne na steroid wanda ake amfani dashi don magance wasu allergies, yanayin kumburi, cututtukan autoimmune, da ciwon daji.^[1][2] Wasu daga cikin waɗannan yanayi sun haɗa da rashin wadatar adrenocortical, hawan jini na calcium, rheumatoid arthritis, dermatitis, kumburin ido, asma, da kuma sclerosis.^[2] Ana amfani da shi ta baki, allura a cikin jijiyoyi, a matsayin cream na fata, da kuma zubar da ido.^[2][3][4]

Prednisolone
type of chemical entity (en)
Bayanai
Ƙaramin ɓangare na	steroid (en)
Amfani	magani
Sinadaran dabara	C₂₁H₂₈O₅
Canonical SMILES (en)	CC12CC(C3C(C1CCC2(C(=O)CO)O)CCC4=CC(=O)C=CC34C)O
Isomeric SMILES (en)	C[C@]12C[C@@H]([C@H]3[C@H]([C@@H]1CC[C@@]2(C(=O)CO)O)CCC4=CC(=O)C=C[C@]34C)O
World Health Organisation international non-proprietary name (en)	prednisolone
Matsalar da zata iya haifarwa	mental depression (en)
Ta jiki ma'amala da	Nuclear receptor subfamily 3 group C member 1 (en) , Nuclear receptor subfamily 3 group C member 2 (en) da Glucocorticoid receptor (en)
Pregnancy category (en)	Australian pregnancy category A (en) da US pregnancy category C (en)
Has characteristic (en)	bitterness (en)
Stylized name (en)	prednisoLONE

Abubuwan da ke haifar da amfani na ɗan gajeren lokaci sun haɗa da tashin zuciya da jin gajiya.^[1] Mafi tsanani illa sun haɗa da matsalolin tabin hankali, wanda zai iya faruwa a cikin kusan 5% na mutane.^[5] Illolin gama gari tare da amfani na dogon lokaci sun haɗa da asarar kashi, rauni, cututtukan yisti, da ƙumburi mai sauƙi.^[2] Yayin da amfani na ɗan gajeren lokaci a cikin ɓangaren baya na ciki yana da lafiya, amfani na dogon lokaci ko amfani da shi a farkon ciki yana da alaƙa da cutarwa ga jariri.^[6] Glucocorticoid ne wanda aka yi daga hydrocortisone (cortisol).^[7]

An gano Prednisolone kuma an yarda da shi don amfani da magani a cikin 1955.^[7] Yana cikin Jerin Mahimman Magunguna na Hukumar Lafiya ta Duniya.^[8] Akwai shi azaman magani na gama-gari. Farashin jimla a cikin ƙasashe masu tasowa kusan dalar Amurka 0.01 akan kowace kwamfutar hannu 5 mg.^[9] A cikin 2017, shi ne na 129th mafi yawan magunguna a Amurka, tare da magunguna fiye da miliyan biyar.^[10][11]

Manazarta

1. World Health Organization (2009). Stuart MC, Kouimtzi M, Hill SR (eds.). WHO Model Formulary 2008. World Health Organization. pp. 53–54. hdl:10665/44053. ISBN 9789241547659.
2. "Prednisolone". The American Society of Health-System Pharmacists. Archived from the original on 23 December 2016. Retrieved 8 December 2016.
3. "Orapred ODT- prednisolone sodium phosphate tablet, orally disintegrating". DailyMed. 11 September 2019. Retrieved 9 March 2020.
4. "Omnipred- prednisolone acetate suspension". DailyMed. 9 September 2019. Retrieved 9 March 2020.
5. "Pevanti 10mg Tablets – Summary of Product Characteristics (SPC) – (eMC)". www.medicines.org.uk. 1 December 2014. Archived from the original on 20 December 2016. Retrieved 13 December 2016.
6. "Prednisolone Use During Pregnancy". Drugs.com. 16 January 2000. Retrieved 9 March 2020.
7. Kim, Kyu-Won; Roh, Jae Kyung; Wee, Hee-Jun; Kim, Chan (2016). Cancer Drug Discovery: Science and History. Springer. p. 169. ISBN 9789402408447. Archived from the original on 2017-09-10.
8. World Health Organization (2019). World Health Organization model list of essential medicines: 21st list 2019. Geneva: World Health Organization. hdl:10665/325771. WHO/MVP/EMP/IAU/2019.06. License: CC BY-NC-SA 3.0 IGO.
9. "Prednisolone" (PDF). WHO International Drug Price Indicator Guide, 2014.
10. "The Top 300 of 2020". ClinCalc. Retrieved 11 April 2020.
11. "Prednisolone - Drug Usage Statistics". ClinCalc. Retrieved 11 April 2020.