konposatu kimiko From Wikipedia, the free encyclopedia
Kinidina agente antiarritmiko gisa jarduten duen sendagai bat da eta, kimikoki, kininaren estereoisomero bat da, kinaren zurtoinen eta sustraien azal disekatuaren jatorrizko deribatua . Bihotz-maiztasun anormalaren eta bihotz-erritmoko beste nahasmendu batzuen tratamenduan adierazten da, bihotza jarduera elektriko anormalarekiko erresistenteagoa eginez[1].
| Kinidina | |
|---|---|
 | |
| Formula kimikoa | C20H24N2O2 |
| SMILES kanonikoa | 2D eredua |
| SMILES isomerikoa | COC1=CC2=C(C=CN=C2C=C1)[C@@H]([C@H]3C[C@@H]4CCN3C[C@@H]4C=C)O |
| MolView | 3D eredua |
| Konposizioa | Nitrogeno eta karbono |
| Mota | [[[(2R,5R)-5-ethenyl-1-azabicyclo[2.2.2]octan-2-yl]-(6-methoxy-4-quinolinyl)methanol|[(2R,5R)-5-ethenyl-1-azabicyclo[2.2.2]octan-2-yl]-(6-methoxy-4-quinolinyl)methanol]] (en)  |
| Ezaugarriak | |
| Fusio-puntua | 170 ℃ |
| Masa molekularra | 324,184 Da |
| Erabilera | |
| Tratatzen du | Aurikulako fibrilazio |
| Interakzioak | moxifloxazino, amiodarone (en) , anagrelide (en) , arsenic trioxide (en) , astemizole (en) , Azitromizina, bepridil (en) , klorokina, klorpromazina, cisapride (en) , (RS)-citalopram (en) , Klaritromizina, kokaina, disopyramide (en) , dofetilide (en) , domperidone (en) , dronedarone (en) , droperidol (en) , Eritromizina, escitalopram (en) , flecainide (en) , halofantrine (en) , haloperidol, ibutilide (en) , mesoridazine (en) , Metadona, Ondansetron, pentamidine (en) , pimozide (en) , probucol (en) , procainamide (en) , sevoflurane (en) , sotalol (en) , sparfloxacin (en) , (RS)-sulpiride (en) , terfenadine (en) eta tioridazina |
| Elkarrekintza | Potassium channel, subfamily U, member 1 (en) , Potassium voltage-gated channel subfamily H member 1 (en) , Potassium voltage-gated channel subfamily H member 5 (en) , Potassium voltage-gated channel subfamily A member 5 (en) , Potassium voltage-gated channel subfamily A member 7 (en) eta Solute carrier family 29 member 4 (en) |
| Haurdunaldia | Australian pregnancy category C (en) eta US pregnancy category C (en) |
| Rola | alpha blocker (en) , antiarrhythmic agent (en) , Entzimen inhibitzaile, cytochrome P-450 CYP2D6 inhibitors (en) , antipaludiko, muscarinic antagonist (en) , voltage-gated sodium channel blockers (en) eta Bakterizida |
| Identifikatzaileak | |
| InChlKey | LOUPRKONTZGTKE-LHHVKLHASA-N |
| CAS zenbakia | 56-54-2 |
| ChemSpider | 389880 |
| PubChem | 441074 |
| Reaxys | 91866 |
| Gmelin | 28593 |
| ChEMBL | CHEMBL1294 |
| ZVG | 36050 |
| EC zenbakia | 200-279-0 |
| ECHA | 100.000.254 |
| MeSH | D011802 |
| RxNorm | 9068 |
| Human Metabolome Database | HMDB0015044 |
| UNII | ITX08688JL |
| NDF-RT | N0000148010 |
| KEGG | C06527 |
| PDB Ligand | QDN |
Seamless Wikipedia browsing. On steroids.
Every time you click a link to Wikipedia, Wiktionary or Wikiquote in your browser's search results, it will show the modern Wikiwand interface.
Wikiwand extension is a five stars, simple, with minimum permission required to keep your browsing private, safe and transparent.
