α-Tocopheryl acetate
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α-Tocopheryl acetate (alpha-tocopherol acetate), also known as vitamin E acetate, is a form of vitamin E with D-Alpha Tocpheryl Acetate as the natural form and DL-Alpha Tocopheryl Acetate as the synthetic form. DL-indicates the synthetic form where as D- indicates the natural form. It is the ester of acetic acid and α-tocopherol.[2]
Names | |
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Preferred IUPAC name
(2R)-2,5,7,8-Tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-3,4-dihydro-2H-1-benzopyran-6-yl acetate | |
Other names
α-Tocopherol acetate Vitamin E acetate | |
Identifiers | |
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3D model (JSmol) |
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ChEMBL | |
ChemSpider |
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DrugBank | |
ECHA InfoCard | 100.000.369 |
PubChem CID |
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UNII | |
CompTox Dashboard (EPA) |
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Properties | |
C31H52O3 | |
Molar mass | 472.743 g/mol |
Appearance | pale yellow, viscous liquid[1] |
Melting point | –27.5 °C[1] |
Boiling point | 240 °C decays without boiling[2] |
insoluble[1] | |
Solubility | soluble in acetone, chloroform, diethyl ether; poorly soluble in ethanol[1] |
Hazards | |
NFPA 704 (fire diamond) | |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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The U.S. Centers for Disease Control and Prevention says that vitamin E acetate is a very strong culprit of concern in the 2019 outbreak of vaping-associated pulmonary injury (VAPI),[3] but there is not yet sufficient evidence to rule out contributions from other chemicals.[4][5] Vaporization of this ester produces toxic pyrolysis products.[6]