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West Virginia Route 75 is an east–west state route in Wayne County, West Virginia. The western terminus of the route is at U.S. Route 60 (Oak Street) in Kenova. From US 60, WV 75 proceeds to the south then east towards its eastern terminus at West Virginia Route 152 north of Lavalette.
_just_north_of_Lavalette_in_Wayne_County,_West_Virginia.jpg)
WV 75 runs concurrent to U.S. Route 52 (Tolsia Highway) from Interstate 64 south for three miles (5 km) to the incomplete diamond interchange.
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The entire route is in Wayne County.
| Location | mi | km | Destinations | Notes | |
|---|---|---|---|---|---|
| Kenova |  US 60 (Oak Street) | ||||
   I-64 / US 52 north – Huntington, Ashland, KY | I-64 exit 1; west end of US 52 overlap | ||||
| |  US 52 south – Williamson | east end of US 52 overlap | |||
| |  WV 152 – Huntington, Wayne | ||||
1.000 mi = 1.609 km; 1.000 km = 0.621 mi
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