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Presence of fluid-filled lesions in the skin or mucous membranes From Wikipedia, the free encyclopedia
A vesiculobullous disease is a type of mucocutaneous disease characterized by vesicles and bullae (i.e. blisters). Both vesicles and bullae are fluid-filled lesions, and they are distinguished by size (vesicles being less than 5–10 mm and bulla being larger than 5–10 mm, depending upon which definition is used). In the case of vesiculobullous diseases which are also immune disorders, the term immunobullous[1] is sometimes used. Examples of vesiculobullous diseases include:
Vesiculobullous disease | |
---|---|
Diagram showing cross section of vesicles (left) and bullae (right) on skin. | |
Specialty | Dermatology |
Some features are as follows:
Name | Acantholysis? | Ig |
---|---|---|
epidermolysis bullosa | yes | mostly IgG |
bullous pemphigoid | no | mostly IgG |
dermatitis herpetiformis | no | IgA |
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