VTA1

Vacuolar protein sorting-associated protein VTA1 homolog is a protein that in humans is encoded by the VTA1 gene.^[5][6]

VTA1
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 2LXL, 2LXM, 4TXP, 4TXQ, 4TXR, 4U7E
Identifiers
Aliases	VTA1, C6orf55, DRG-1, DRG1, LIP5, My012, SBP1, HSPC228, vesicle trafficking 1, 6orf55
External IDs	OMIM: 610902; MGI: 1913451; HomoloGene: 6473; GeneCards: VTA1; OMA:VTA1 - orthologs
Gene location (Human) Chr. Chromosome 6 (human)[1] Band 6q24.1-q24.2 Start 142,147,162 bp[1] End 142,224,685 bp[1]
Gene location (Mouse) Chr. Chromosome 10 (mouse)[2] Band 10|10 A2 Start 14,530,499 bp[2] End 14,581,304 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in ganglionic eminence pancreatic epithelial cell amniotic fluid deltoid muscle ventricular zone tibialis anterior muscle islet of Langerhans vastus lateralis muscle skin of arm mucosa of ileum Top expressed in zygote medial ganglionic eminence secondary oocyte genital tubercle neural layer of retina tail of embryo granulocyte primary oocyte dentate gyrus of hippocampal formation granule cell right kidney More reference expression data BioGPS n/a
Gene ontology Molecular function protein C-terminus binding protein binding Cellular component cytoplasm cytosol endosome endosome membrane extracellular exosome membrane nucleoplasm intracellular membrane-bounded organelle Biological process protein transport endosomal transport multivesicular body assembly viral life cycle multivesicular body sorting pathway ESCRT III complex disassembly macroautophagy transport Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 51534 66201 Ensembl ENSG00000009844 ENSMUSG00000019868 UniProt Q9NP79 Q9CR26 RefSeq (mRNA) NM_016485 NM_001286371 NM_001286372 NM_025418 RefSeq (protein) NP_001273300 NP_001273301 NP_057569 NP_079694 Location (UCSC) Chr 6: 142.15 – 142.22 Mb Chr 10: 14.53 – 14.58 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

References

1. GRCh38: Ensembl release 89: ENSG00000009844 – Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000019868 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Shi J, Cai W, Chen X, Ying K, Zhang K, Xie Y (Aug 2001). "Identification of dopamine responsive mRNAs in glial cells by suppression subtractive hybridization". Brain Res. 910 (1–2): 29–37. doi:10.1016/S0006-8993(01)02393-9. PMID 11489251. S2CID 43814085.
6. "Entrez Gene: C6orf55 chromosome 6 open reading frame 55".

Further reading

• Andersson B, Wentland MA, Ricafrente JY, et al. (1996). "A "double adaptor" method for improved shotgun library construction". Anal. Biochem. 236 (1): 107–13. doi:10.1006/abio.1996.0138. PMID 8619474.
• Yu W, Andersson B, Worley KC, et al. (1997). "Large-scale concatenation cDNA sequencing". Genome Res. 7 (4): 353–8. doi:10.1101/gr.7.4.353. PMC 139146. PMID 9110174.
• Zhang QH, Ye M, Wu XY, et al. (2001). "Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells". Genome Res. 10 (10): 1546–60. doi:10.1101/gr.140200. PMC 310934. PMID 11042152.
• Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072. PMID 11230166.
• Tchernev VT, Mansfield TA, Giot L, et al. (2002). "The Chediak-Higashi protein interacts with SNARE complex and signal transduction proteins". Mol. Med. 8 (1): 56–64. doi:10.1007/bf03402003. PMC 2039936. PMID 11984006.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
• Fujita H, Umezuki Y, Imamura K, et al. (2005). "Mammalian class E Vps proteins, SBP1 and mVps2/CHMP2A, interact with and regulate the function of an AAA-ATPase SKD1/Vps4B". J. Cell Sci. 117 (Pt 14): 2997–3009. doi:10.1242/jcs.01170. PMID 15173323.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. Bibcode:2005Natur.437.1173R. doi:10.1038/nature04209. PMID 16189514. S2CID 4427026.