Loading AI tools
From Wikipedia, the free encyclopedia
U12 minor spliceosomal RNA is formed from U12 small nuclear (snRNA), together with U4atac/U6atac, U5, and U11 snRNAs and associated proteins, forms a spliceosome that cleaves a divergent class of low-abundance pre-mRNA introns. Although the U12 sequence is very divergent from that of U2, the two are functionally analogous.[1]
U12 minor spliceosomal RNA | |
---|---|
Identifiers | |
Symbol | U12 |
Rfam | RF00007 |
Other data | |
RNA type | Gene; snRNA; splicing |
Domain(s) | Eukaryota |
GO | GO:0000371 GO:0045131 GO:0005693 |
SO | SO:0000399 |
PDB structures | PDBe |
The predicted secondary structure of U12 RNA is published,.[2] However, the alternative single hairpin in the 3' end shown here seems to better match the alignment of divergent Drosophila melanogaster and Arabidopsis thaliana sequences.[3] The sequences U12 introns that are spliced out are collected in a biological database called the U12 intron database.
Seamless Wikipedia browsing. On steroids.
Every time you click a link to Wikipedia, Wiktionary or Wikiquote in your browser's search results, it will show the modern Wikiwand interface.
Wikiwand extension is a five stars, simple, with minimum permission required to keep your browsing private, safe and transparent.