Tiazesim

Tiazesim (INNTooltip International Nonproprietary Name), or thiazesim (BANTooltip British Approved Name, USANTooltip United States Adopted Name), previously sold under the brand name Altinil, is a heterocyclic antidepressant related to the tricyclic antidepressants (TCAs) which, introduced in 1966 by Squibb Corporation (now Bristol-Myers Squibb), has since been discontinued and is no longer marketed.^[1][2]

Tiazesim

Clinical data
Trade names	Altinil
Other names	Thiazesim; Thiazenone; SQ-10496
Routes of administration	By mouth
ATC code	None
Legal status
Legal status	In general: ℞ (Prescription only)
Identifiers
IUPAC name 5-[2-(dimethylamino)ethyl]-2-phenyl-2,3-dihydro-1,5-benzothiazepin-4(5H)-one
CAS Number	5845-26-1 3122-01-8 (hydrochloride)
PubChem CID	22107
ChemSpider	20775 Y
UNII	44G76ZB85O
KEGG	D02699 Y
ChEMBL	ChEMBL2111123 Y
CompTox Dashboard (EPA)	DTXSID30863620
Chemical and physical data
Formula	C19H22N2OS
Molar mass	326.46 g·mol−1
3D model (JSmol)	Interactive image
SMILES CN(C)CCN1C(=O)CC(SC2=CC=CC=C21)C3=CC=CC=C3
InChI InChI=1S/C19H22N2OS/c1-20(2)12-13-21-16-10-6-7-11-17(16)23-18(14-19(21)22)15-8-4-3-5-9-15/h3-11,18H,12-14H2,1-2H3 Key:QJJXOEFWXSQISU-UHFFFAOYSA-N

See also

• Diltiazem
• Tofenacin

References

1. Ganellin CR, Triggle DJ, Macdonald F (1997). Dictionary of pharmacological agents. CRC Press. p. 1973. ISBN 978-0-412-46630-4. Retrieved 29 November 2011.
2. The United States patents quarterly. 1969. OCLC 1768767. Retrieved 1 May 2012.