Thienobenzodiazepine

Thienobenzodiazepine is a heterocyclic compound containing a diazepine ring fused to a thiophene ring and a benzene ring. Thienobenzodiazepine forms the central core of pharmaceutical drugs including atypical antipsychotic olanzapine (Zyprexa) and antimuscarinic telenzepine. Thienobenzodiazepines act relatively selectively at the α₂ subunit of the GABA_A receptor.^[1]

Not to be confused with thienodiazepine or thienotriazolodiazepine.

General structure of thienobenzodiazepines. Core is highlighted by black and color. Grey depicts accessory functional groups.