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| TVyNovelas Award for Best Leading Actress | |
|---|---|
| Awarded for | Best performance by an actress in a leading role |
| First awarded | 1986 Magda Guzmán Tú o nadie |
| Currently held by | 2020 Arcelia Ramírez Vencer el miedo |
1980s
| Winner | Nominated | |||||||
|---|---|---|---|---|---|---|---|---|
| 4th TVyNovelas Awards | ||||||||
 |
Magda Guzmán for Tú o nadie |
| ||||||
| 5th TVyNovelas Awards | ||||||||
|
María Rubio for Cuna de Lobos |
| ||||||
| 6th TVyNovelas Awards | ||||||||
|
Rosario Gálvez for Victoria | |||||||
| 7th TVyNovelas Awards | ||||||||
 |
Jacqueline Andere for Nuevo amanecer | |||||||
1990s
| Winner | Nominated | |||||||
|---|---|---|---|---|---|---|---|---|
| 8th TVyNovelas Awards | ||||||||
|
Patricia Reyes Spíndola for Teresa | |||||||
| 9th TVyNovelas Awards | ||||||||
|
Ofelia Guilmáin for Días sin luna | |||||||
| 10th TVyNovelas Awards | ||||||||
|
Irán Eory for La Pícara Soñadora |
| ||||||
| 11th TVyNovelas Awards | ||||||||
|
Ada Carrasco for De frente al sol | |||||||
| 12th TVyNovelas Awards | ||||||||
|
Claudia Islas for Corazón salvaje |
| ||||||
| 13th TVyNovelas Awards | ||||||||
|
Jacqueline Andere for El vuelo del águila |
| ||||||
| 14th TVyNovelas Awards | ||||||||
 |
Marga López for Lazos de Amor | |||||||
| 15th TVyNovelas Awards | ||||||||
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Angélica María for Bendita mentira | |||||||
| 16th TVyNovelas Awards | ||||||||
|
Jacqueline Andere for Mi querida Isabel | |||||||
| 17th TVyNovelas Awards | ||||||||
|
Marga López for El Privilegio de Amar | |||||||
2000s
| Winner | Nominated | |||||||
|---|---|---|---|---|---|---|---|---|
| 18th TVyNovelas Awards | ||||||||
|
Norma Herrera for Tres mujeres |
| ||||||
| 19th TVyNovelas Awards | ||||||||
 |
Helena Rojo for Abrázame muy fuerte | |||||||
| 20th TVyNovelas Awards | ||||||||
|
Daniela Romo for El Manantial | |||||||
| 21st TVyNovelas Awards | ||||||||
|
Jacqueline Andere for La Otra |
| ||||||
| 22nd TVyNovelas Awards | ||||||||
|
Ana Martín for Amor Real | |||||||
| 24th TVyNovelas Awards | ||||||||
 |
Delia Casanova for La esposa virgen |
| ||||||
| 25th TVyNovelas Awards | ||||||||
|
Helena Rojo for Mundo de fieras | |||||||
| 26th TVyNovelas Awards | ||||||||
|
Ana Martín for Destilando Amor | |||||||
| 27th TVyNovelas Awards | ||||||||
|
Helena Rojo for Cuidado con el ángel |
| ||||||
2010s
2020s
| Winner | Nominated | |||||||
|---|---|---|---|---|---|---|---|---|
| 38th TVyNovelas Awards[5] | ||||||||
 |
Arcelia Ramírez for Vencer el miedo | |||||||
- Most awarded actress: Jacqueline Andere and Helena Rojo, 4 times.
- Most nominated actress: Helena Rojo with 8 nominations.
- Most nominated actress without a win: Ana Bertha Espín with 4 nominations.
- Youngest winner: Patricia Reyes Spíndola, 36 years old.
- Youngest nominee: Daniela Castro, 40 years old.
- Oldest winner: Silvia Pinal, 86 years old.
- Oldest nominee: Libertad Lamarque, 91 years old.
- Actresses that winning the award for the same role: Magda Guzmán (Tú o nadie, 1986) and Daniela Romo (Sortilegio, 2010)
- Actress winning after short time: Helena Rojo by (Mundo de fieras, 2007) and (Cuidado con el ángel, 2009), 2 years difference.
- Actress winning after long time: Magda Guzmán by (Tú o nadie, 1986) and (Para volver a amar, 2011), 25 years difference.
- Actresses winning this category, despite having been as a main villain:
- María Rubio (Cuna de lobos, 1987)
- Ofelia Guilmáin (Días sin luna, 1991)
- Claudia Islas (Corazón salvaje, 1994)
- Jacqueline Andere (Mi querida Isabel, 1998)
- Marga López (El Privilegio de Amar, 1999)
- Helena Rojo (Abrázame muy fuerte, 2001)
- Daniela Romo (El Manantial, 2002)
- Jacqueline Andere (La Otra, 2003)
- Helena Rojo (Mundo de fieras, 2007)
- Blanca Guerra (Abismo de pasión, 2013)
- Rosa María Bianchi (Yo no creo en los hombres, 2015)
- Actresses was nominated in this category, despite having played as a main villain:
- Surya MacGregor (Martín Garatuza, 1987)
- Martha Roth (El pecado de Oyuki, 1989)
- Susana Alexander (Susana Alexander, 1991)
- María Teresa Rivas (Agujetas de color de rosa, 1994)
- Angélica Aragón (Cañaveral de pasiones, 1997)
- Beatriz Aguirre (Sin pecado concebido, 2002)
- Silvia Pasquel (Amarte es mi pecado, 2004)
- Diana Bracho (Heridas de amor, 2007)
- Helena Rojo (Corazón salvaje, 2010)
- Daniela Castro (Mi pecado, 2010)
- Laura Zapata (Zacatillo, un lugar en tu corazón, 2011)
- Lucía Méndez (Esperanza del corazón, 2012)
- Ana Bertha Espín (La que no podía amar, 2012)
- Foreign winning actress:
- Ofelia Guilmáin from Spain
- Irán Eory from Iran
- Marga López from Argentina
- Angélica María from United States
- Rosa María Bianchi from Argentina
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