TRPC4AP

Trpc4-associated protein is a protein that in humans is encoded by the TRPC4AP gene.

TRPC4AP
Identifiers
Aliases	TRPC4AP, C20orf188, PPP1R158, TRRP4AP, TRUSS, transient receptor potential cation channel subfamily C member 4 associated protein
External IDs	OMIM: 608430; MGI: 1930751; HomoloGene: 9224; GeneCards: TRPC4AP; OMA:TRPC4AP - orthologs
Gene location (Human) Chr. Chromosome 20 (human)[1] Band 20q11.22 Start 35,002,404 bp[1] End 35,092,807 bp[1]
Gene location (Mouse) Chr. Chromosome 2 (mouse)[2] Band 2 H1|2 77.26 cM Start 155,476,191 bp[2] End 155,534,304 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in granulocyte right adrenal cortex anterior pituitary gastric mucosa body of pancreas left adrenal gland stromal cell of endometrium left adrenal cortex gastrocnemius muscle upper lobe of left lung Top expressed in spermatocyte muscle of thigh entorhinal cortex thymus perirhinal cortex CA3 field granulocyte cerebellar cortex superior frontal gyrus dentate gyrus of hippocampal formation granule cell More reference expression data BioGPS More reference expression data
Gene ontology Molecular function phosphatase binding protein binding calcium channel activity Cellular component plasma membrane Cul4A-RING E3 ubiquitin ligase complex Biological process calcium ion transmembrane transport protein ubiquitination hair follicle maturation ubiquitin-dependent protein catabolic process Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 26133 56407 Ensembl ENSG00000100991 ENSMUSG00000038324 UniProt Q8TEL6 Q9JLV2 RefSeq (mRNA) NM_015638 NM_199368 NM_001163452 NM_019828 RefSeq (protein) NP_056453 NP_955400 NP_001156924 NP_062802 Location (UCSC) Chr 20: 35 – 35.09 Mb Chr 2: 155.48 – 155.53 Mb PubMed search [3] [4]
Wikidata
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Interactions

TRPC4AP has been shown to interact with TNFRSF1A.^{[5][clarification needed]}

See also

• TRPC

References

1. GRCh38: Ensembl release 89: ENSG00000100991 – Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000038324 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Soond SM, Terry JL, Colbert JD, Riches DW (Nov 2003). "TRUSS, a novel tumor necrosis factor receptor 1 scaffolding protein that mediates activation of the transcription factor NF-kappaB". Mol. Cell. Biol. 23 (22): 8334–44. doi:10.1128/MCB.23.22.8334-8344.2003. PMC 262424. PMID 14585990.