Sulforhodamine 101

Sulforhodamine 101 (SR101) is a red fluorescent dye. In neurophysiological experiments which comprise calcium imaging methods, it can be used for a counterstaining of astrocytes to be able to analyze data from neurons separately.^[1] However, in addition to labeling astrocytes, SR101 labels myelinating oligodendrocytes.^[2] SR101 has been reported to affect excitability of neurons and should therefore be used with caution.^[3]

Sulforhodamine 101

Identifiers
CAS Number	60311-02-6 Y
3D model (JSmol)	Interactive image
Beilstein Reference	3582548
ECHA InfoCard	100.056.491
PubChem CID	122180
UNII	FX0ES3271V Y
CompTox Dashboard (EPA)	DTXSID00922157
SMILES [O-]S(C(C=C(S(O)(=O)=O)C=C1)=C1C2=C(C=C3C4=C5CCCN4CCC3)C5=[O+]C6=C(CCCN7CCC8)C7=C8C=C62)(=O)=O
Properties
Chemical formula	C31H30N2O7S2
Molar mass	606.71 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Y verify (what is YN ?) Infobox references

A sulfonyl chloride derivative of sulforhodamine 101, known as Texas Red, is used for conjugation to a number of functional groups, especially primary amines.