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Medical condition From Wikipedia, the free encyclopedia
Sporadic hemiplegic migraine (SHM) is a form of hemiplegic migraine headache isolated cases of which are observed.[1] It is a rare disease. It is considered to be a separate type of migraine.[2]
| Sporadic hemiplegic migraine | |
|---|---|
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| This condition is inherited in an autosomal dominant manner |
Sporadic hemiplegic migraine (SHM) has clinical symptoms identical to familial hemiplegic migraine (FHM) and distinct from migraine with aura. By definition the neurodeficits are supposed to be reversible. However, some cases with permanent neurological deficits have also been noted.[3]
CACNA1A, ATP1A2 and SCNA1 are genes associated with hemipeligic migraines, although many cases are considered idiopathic with no known cause. [4]
Diagnostic criteria require motor symptoms and at least one visual, sensory, or speech symptom, resembling basilar migraine.[5] They may also be associated with cerebellar signs.[6]
MRI features can be suggestive of cortical infarction and edema.[7]
Differential diagnoses can be:[5]
![[icon]](#/media/File:Wiki_letter_w_cropped.svg){kind=small} | This section is empty. You can help by adding to it. (August 2017) |
Prevalence is estimated to be 0.005%.[8] The age of onset has been found to be under 15 years in 40% of cases while it is between 10 and 14 years in one third of the cases. Females outnumber males, 4 to 1. Only 3% have attacks after age 52.[2]
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