Sebaceous adenoma

Sebaceous adenomais a type of adenoma, characterized by a slow-growing tumor usually presenting as a pink, flesh-coloured, or yellow papule or nodule.^{[1]: 662 [2]}

Sebaceous adenoma
Micrograph of a sebaceous adenoma. H&E stain.
Specialty	Dermatology

Significance

Sebaceous adenomas, in isolation, are not significant; however, they may be associated with Muir-Torre syndrome, a genetic condition that predisposes individuals to cancer.^[3] It is also linked to hereditary nonpolyposis colorectal cancer (Lynch syndrome).^{[citation needed]}

It is not the same as "adenoma sebaceum" by F. Balzer and P.E. Ménétrier (1885).^[4] The term "adenoma sebaceum" is a misnomer for facial angiofibromas associated with tuberous sclerosis complex.^[5][a][b]

See also

• Sebaceous carcinoma
• Sebaceous hyperplasia
• List of cutaneous conditions
• List of cutaneous neoplasms associated with systemic syndromes

Notes

1. Balzer and Menetrier (1885) described the microscopic appearance of the facial papules as "adenoma sebaceum", thought to be benign tumors of sebaceous glands, although the skin lesions are angiofibromas.
2. Facial angiofibromas were first described in 1885 by Balzer and Menetrier. At this time, they were incorrectly termed adenoma sebaceum. We now know that the sebaceous glands are only passively involved, if at all. Facial angiofibromas are hamartomas, defined as benign, tumorous nodules of superfluous tissue.